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TSFM 抗体 (N-Term)

TSFM 适用: 人, 小鼠, 大鼠, Cow, 犬, 斑马鱼, 非洲爪蟾 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN1109361
发货至: 中国
  • 抗原 See all TSFM 抗体
    TSFM (Ts Translation Elongation Factor, Mitochondrial (TSFM))
    抗原表位
    • 9
    • 8
    • 6
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    适用
    • 31
    • 7
    • 6
    • 5
    • 5
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    人, 小鼠, 大鼠, Cow, 犬, 斑马鱼, 非洲爪蟾
    宿主
    • 28
    • 3
    克隆类型
    • 29
    • 2
    多克隆
    标记
    • 21
    • 2
    • 2
    • 2
    • 2
    • 2
    This TSFM antibody is un-conjugated
    应用范围
    • 30
    • 18
    • 6
    • 3
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    序列
    KQAEIWLHKE AQKEGWSKAA KLQGRKTKEG LIGLLQEGNT TVLVEVNCET
    交叉反应 (详细)
    Species reactivity (expected):Mouse, Rat, Dog, African clawed frog, Bovine, ZebrafishSpecies reactivity (tested):Human
    纯化方法
    Purified using peptide immunoaffinity column
    免疫原
    The immunogen for anti-TSFM antibody: synthetic peptide directed towards the N terminal of human TSFM.
    Top Product
    Discover our top product TSFM Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 溶解方式
    Add 50 μL of distilled water to a final concentration of 1 mg/mL.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store lyophilized at 2-8 °C or at -20 °C long term. After reconstitution store the antibody undiluted at 2-8 °C for up to one month or in aliquots at -20 °C long term.
  • 抗原
    TSFM (Ts Translation Elongation Factor, Mitochondrial (TSFM))
    别名
    TSFM (TSFM 产品)
    别名
    EF-Ts antibody, EF-TsMt antibody, EFTS antibody, zgc:158429 antibody, EFTSMT antibody, 2310050B20Rik antibody, 9430024O13Rik antibody, EF-TS antibody, EF-Tsmt antibody, 2A3-2 antibody, Elongation factor Ts, mitochondrial antibody, Ts translation elongation factor, mitochondrial antibody, Ts translation elongation factor, mitochondrial L homeolog antibody, pco103788 antibody, tsfm antibody, tsfm.L antibody, TSFM antibody, Tsfm antibody
    背景
    The TSFM gene encodes a protein that is expressed in all tissues, with the highest levels of expression in skeletal muscle, liver, and kidney. It associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome. Defects in TSFM are the cause of combined oxidative phosphorylation deficiency type 3 (COXPD3). Defects in the mitochondrial oxidative phosphorylation system result in devastating, mainly multisystem, diseases. COXPD3 symptoms include severe metabolic acidosis with encephalomyopathy or with hypertrophic cardiomyopathy. Patients show a severe defect in mitochondrial translation leading to a failure to assemble adequate amounts of three of the oxidative phosphorylation complexesSynonyms: EF-Ts, EF-TsMt, Elongation factor Ts mitochondrial
    基因ID
    10102
    NCBI登录号
    NP_005717
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