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SYT1 抗体

SYT1 适用: 大鼠 WB, IF, IP 宿主: 小鼠 Monoclonal 1D12 unconjugated
产品编号 ABIN1109184
发货至: 中国
  • 抗原 See all SYT1 抗体
    SYT1 (Synaptotagmin I (SYT1))
    适用
    • 79
    • 70
    • 48
    • 11
    • 7
    • 6
    • 6
    • 4
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    大鼠
    宿主
    • 91
    • 12
    • 6
    • 1
    • 1
    • 1
    小鼠
    克隆类型
    • 100
    • 12
    单克隆
    标记
    • 67
    • 8
    • 6
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SYT1 antibody is un-conjugated
    应用范围
    • 67
    • 41
    • 35
    • 16
    • 13
    • 13
    • 13
    • 10
    • 6
    • 6
    • 4
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP)
    特异性
    This antibody reacts with Synaptotagmin 1 and 2 (58 kDa/60 kDa) on Western blotting. Synaptotagmin 1 has a predicted molecular weight of 47 kDa but it migrates at ~65 kDa. It is reported that this clone (1D12) recognizes rat synaptotagmin residues (99-104 aa) in the reference number 17).
    交叉反应 (详细)
    Species reactivity (tested):Rat
    纯化方法
    Protein A agarose
    免疫原
    Chicken brain synaptic membrane
    克隆位点
    1D12
    亚型
    IgG2a
    Top Product
    Discover our top product SYT1 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    PBS containing 50 % glycerol, pH 7.2, without preservatives
    储存液
    Without preservative
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    -20 °C
    储存方法
    Store (in aliquots) at -20 °C.
  • 抗原
    SYT1 (Synaptotagmin I (SYT1))
    别名
    Synaptotagmin-1 (SYT1 产品)
    背景
    Synaptotagmins are a family of at least 15 Ca2+-binding, membrane-trafficking proteins that act as calcium sensors regulating neurotransmitter release. Synaptotagamins are expressed in both vesicular and plasma membranes where they are involved in lipid rearrangements required during synaptic vesicle fusion. Synaptotagmins also interact with calcium channels, sodium channels, b-SNAP, neurexins, and other neural proteins in the absence of Ca2+, suggesting a role in presynaptic functions. Synaptotagmins exhibit differential expression, with synaptotagmins 1-5 expressed primarily in neural and endocrine tissues. Northern blots in murine brain tissue suggest synaptotagmin 1 is primarily expressed in rostral brain regions but has low expression in regions related to motor functions.Synonyms: SVP65, SYT, SYT2, Synaptotagmin I, Synaptotagmin II, Synaptotagmin1, Synaptotagmin2, Synonyms: SYT1, SytI, SytII, p65
    基因ID
    6857
    NCBI登录号
    NP_001129277
    UniProt
    P21579
    途径
    Synaptic Vesicle Exocytosis, Dicarboxylic Acid Transport
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