CT5.2 antibody, CT5.2A antibody, HD21 antibody, HOM-MEL-40 antibody, SSX antibody, SSX2 antibody, SSX3 antibody, SSX family member 2 antibody, protein SSX2 antibody, synovial sarcoma, X breakpoint 2 antibody, SSX2 antibody, LOC741661 antibody, Ssx2 antibody
背景
Synovial sarcoma, X breakpoint 2, also known as SSX2, is a human gene. The product of this gene elongs to the family of highly homologous synovial sarcoma X (SSX) breakpoint proteins. SSX1, SSX2 nd SSX4 genes have been involved in the t(X,18) translocation characteristically found in all synovial arcomas. The SSX1 and SSX2 genes encode closely related proteins (81 % identity) of 188 amino cids that are rich in charged amino acids. The N-terminal portion of each SSX protein exhibits omology to the Kruppel-associated box (KRAB), a transcriptional repressor domain previously found nly in Kruppel-type zinc finger proteins.Synonyms: CT5.2, Cancer/testis antigen 5.2, HOM-MEL-40, SSX2A, SSX2B, Synovial sarcoma X breakpoint 2