RAF1 抗体
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- 抗原 See all RAF1 抗体
- RAF1 (V-Raf-1 Murine Leukemia Viral Oncogene Homolog 1 (RAF1))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This RAF1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS), Enzyme Immunoassay (EIA)
- 特异性
- This antibody recognizes RAF1
- 交叉反应 （详细）
- Species reactivity (tested):Human.
- 纯化方法
- Purified
- 克隆位点
- 4G4
- 亚型
- IgG1
- Top Product
- Discover our top product RAF1 Primary Antibody
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anti-V-Raf-1 Murine Leukemia Viral Oncogene Homolog 1 (RAF1) (AA 31-130) antibody
RAF1 适用: 人 ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-V-Raf-1 Murine Leukemia Viral Oncogene Homolog 1 (RAF1) (AA 190-350) antibodyRAF1 适用: 人 WB, IHC, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-V-Raf-1 Murine Leukemia Viral Oncogene Homolog 1 (RAF1) (AA 1-130) antibodyRAF1 适用: 人 WB, ELISA, RNAi, PLA 宿主: 小鼠 Monoclonal 1H4 unconjugated
anti-V-Raf-1 Murine Leukemia Viral Oncogene Homolog 1 (RAF1) antibodyRAF1 适用: 人 WB, ELISA, IHC, FACS 宿主: 小鼠 Monoclonal 4G4 unconjugated
anti-V-Raf-1 Murine Leukemia Viral Oncogene Homolog 1 (RAF1) (pSer621) antibodyRAF1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-V-Raf-1 Murine Leukemia Viral Oncogene Homolog 1 (RAF1) (pSer259) antibodyRAF1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-V-Raf-1 Murine Leukemia Viral Oncogene Homolog 1 (RAF1) (AA 1-648) antibodyRAF1 适用: 人 WB, ELISA, IHC, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-V-Raf-1 Murine Leukemia Viral Oncogene Homolog 1 (RAF1) antibodyRAF1 适用: 人, 小鼠, 大鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-V-Raf-1 Murine Leukemia Viral Oncogene Homolog 1 (RAF1) (pSer338) antibodyRAF1 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-V-Raf-1 Murine Leukemia Viral Oncogene Homolog 1 (RAF1) (pSer621) antibodyRAF1 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1.0 mg/mL
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- 抗原
- RAF1 (V-Raf-1 Murine Leukemia Viral Oncogene Homolog 1 (RAF1))
- 别名
- RAF1 (RAF1 产品)
- 背景
- This gene is the cellular homolog of viral raf gene (v-raf). The encoded protein is a MAP kinase kinase kinase (MAP3K), which functions downstream of the Ras family of membrane associated GTPases to which it binds directly. Once activated, the cellular RAF1 protein can phosphorylate to activate the dual specificity protein kinases MEK1 and MEK2, which in turn phosphorylate to activate the serine/threonine specific protein kinases, ERK1 and ERK2. Activated ERKs are pleiotropic effectors of cell physiology and play an important role in the control of gene expression involved in the cell division cycle, apoptosis, cell differentiation and cell migration. Mutations in this gene are associated with Noonan syndrome 5 and LEOPARD syndrome 2.Synonyms: C-RAF, RAF proto-oncogene serine/threonine-protein kinase, Raf-1, cRaf
- 基因ID
- 5894
- 途径
- MAPK Pathway, RTK signaling, Fc-epsilon Receptor Signaling Pathway, Neurotrophin Signaling Pathway, cAMP Metabolic Process, Stem Cell Maintenance, Hepatitis C, Autophagy, Signaling of Hepatocyte Growth Factor Receptor, VEGF Signaling, BCR Signaling
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