电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

p53 抗体

This anti-p53 antibody is a 小鼠 单克隆 antibody detecting p53 in WB, IF, IHC (p) 和 IHC (fro). Suitable for 人.
产品编号 ABIN1108553
发货至: 中国

Quick Overview for p53 抗体 (ABIN1108553)

抗原

See all p53 (TP53) 抗体
p53 (TP53) (Tumor Protein P53 (TP53))

适用

  • 958
  • 277
  • 229
  • 140
  • 74
  • 72
  • 57
  • 39
  • 10
  • 9
  • 9
  • 6
  • 5
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1

宿主

  • 671
  • 313
  • 5
  • 2
  • 2
小鼠

克隆类型

  • 576
  • 416
  • 1
单克隆

标记

  • 520
  • 51
  • 31
  • 20
  • 19
  • 17
  • 17
  • 17
  • 17
  • 17
  • 17
  • 17
  • 14
  • 14
  • 14
  • 14
  • 14
  • 14
  • 14
  • 14
  • 14
  • 12
  • 11
  • 11
  • 11
  • 11
  • 11
  • 11
  • 11
  • 10
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
This p53 antibody is un-conjugated

应用范围

  • 727
  • 322
  • 287
  • 238
  • 210
  • 141
  • 129
  • 127
  • 122
  • 119
  • 80
  • 60
  • 32
  • 20
  • 17
  • 12
  • 10
  • 9
  • 8
  • 6
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

克隆位点

IMD-53
  • 特异性

    This antibody reacts to p53 (TP53).

    纯化方法

    Affinity Chromatography

    免疫原

    Recombinant Human wild-type p53 protein.

    亚型

    IgG2a
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 溶解方式

    Restore with 1.2 % Sodium Acetate or neutral PBS

    浓度

    0.1 mg/mL

    缓冲液

    1.2 % Sodium Acetate with 2 mg BSA and 0.01 mg Sodium Azide as preservative

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    -20 °C

    储存方法

    Prior to reconstitution store at -20 °C. Following reconstitution store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    p53 (TP53) (Tumor Protein P53 (TP53))

    别名

    p53 (TP53)

    背景

    The p53 tumor antigen is found in increased amounts in a wide variety of transformed cells. The protein is also detectable in many actively proliferating, nontransformed cells, but it is undetectable or present at low levels in resting cells. This protein induces cell cycle arrest or apoptosis in response to sublethal or severe DNA damage, respectively, by differential transcription of target genes and through transcription-independent apoptotic functions. The p53 protein contains 393 amino acids. Human p53 tumour antigen is Locatedto band 17p13. p53 mutations are common in pancreatic cancer and are absent in chronic pancreatitis.Synonyms: Cellular tumor antigen p53, NY-CO-13, Phosphoprotein p53, Tumor suppressor p53

    基因ID

    7157

    NCBI登录号

    NP_000537

    UniProt

    P04637

    途径

    p53 Pathway, MAPK Pathway, PI3K-Akt Signaling, Apoptosis, AMPK Signaling, Chromatin Binding, ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Hepatitis C, Protein targeting to Nucleus, Autophagy, Warburg Effect
You are here:
Chat with us!