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Ly6g 抗体 (FITC)

Ly6g 适用: 小鼠 IHC (fro), Func, IHC (p), EIA 宿主: 大鼠 Monoclonal NIMP-R14 FITC
产品编号 ABIN1108441
发货至: 中国
  • 抗原 See all Ly6g products
    Ly6g (Lymphocyte Antigen 6 Complex, Locus G (Ly6g))
    适用
    • 83
    • 13
    小鼠
    宿主
    • 64
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    大鼠
    克隆类型
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    单克隆
    标记
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    This Ly6g antibody is conjugated to FITC
    应用范围
    • 63
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    Immunohistochemistry (Frozen Sections) (IHC (fro)), Functional Studies (Func), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    交叉反应 (详细)
    Species reactivity (tested):Mouse
    纯化方法
    Protein G
    免疫原
    Purified BALB/c mouse neutrophils
    克隆位点
    NIMP-R14
    亚型
    IgG2b
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 浓度
    0.1 mg/mL
    缓冲液
    PBS, 0.02 % Sodium Azide, 1.0 % BSA
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    Store at 2 - 8 °C.
  • 抗原
    Ly6g (Lymphocyte Antigen 6 Complex, Locus G (Ly6g))
    别名
    Ly6G / GR1 Neutrophil Marker (Ly6g 产品)
    别名
    Gr-1 antibody, Gr1 antibody, Ly-6G antibody, lymphocyte antigen 6 complex, locus G antibody, Ly6g antibody
    背景
    The Ly-6G/-6C locus encodes a family of Ly-6 proteins including Ly-6G and Ly-6C. Ly-6 antigens have a molecular weight between 15,000 and 18,000. Ly6G is together with Ly6c a component of the myeloid differentiation antigen Gr-1. Ly6G a GPI-anchored protein and is a good marker of peripheral neutrophils. Although predominantly presents on neutrophils, it is also expressed on a subset of eosinophils, differentiating pre-monocytes and plasmacytoid dendritic cells. Ly6C is a monocyte/macrophage and endothelial cell differentiation antigen regulated by interferon gamma, and may play a role in the development and maturation of lymphocytes. It is expressed on bone marrow cells, monocytes/macrophages, neutrophils, endothelial cells, and T cell subsets. Expression of Gr-1 in bone marrow correlates with granulocyte differentiation and maturation. However, the physiological role of Ly6G alone remains still unclear.Synonyms: Gr-1 Granulocyte marker
    基因ID
    10090
    UniProt
    P35461
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