MTDH 抗体
Quick Overview for MTDH 抗体 (ABIN1108306)
抗原
See all MTDH 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- This antibody reacts to Metadherin.
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交叉反应 （详细）
- Species reactivity (tested):Human.
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纯化方法
- Affinity chromatography on Protein G
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亚型
- IgG1
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anti-Metadherin (MTDH) antibody
MTDH 适用: 人 WB, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-Metadherin (MTDH) (AA 101-270) antibodyMTDH 适用: 人, 小鼠, 大鼠 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated
anti-Metadherin (MTDH) antibodyMTDH 适用: 人, 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Metadherin (MTDH) (AA 1-582) antibodyMTDH 适用: 人 WB, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-Metadherin (MTDH) (AA 1-582) antibodyMTDH 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Metadherin (MTDH) antibodyMTDH 适用: 人 WB, IHC, ELISA, FACS 宿主: 小鼠 Monoclonal 2F11C3 unconjugated
anti-Metadherin (MTDH) (AA 101-270) antibodyMTDH 适用: 人, 小鼠, 大鼠 WB, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-Metadherin (MTDH) (AA 1-260) antibodyMTDH 适用: 人 IHC, ELISA, IP 宿主: 兔 Polyclonal unconjugated
anti-Metadherin (MTDH) (AA 131-230) antibodyMTDH 适用: 人 WB, ELISA, FACS, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS, 0,03 % sodium azide, 50 % glycerol
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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- MTDH (Metadherin (MTDH))
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别名
- MTDH
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背景
- Metadherin (Metastasis adhesion protein), also known as MTDH, LYsine-RIch CEACAM1 co-isolated (LYRIC), is a novel protein that localizes with the tight junction proteins ZO-1 and occludin in polarized epithelial cells. At the tight junction, it acts not as a structural component, but is rather recruited during the maturation of the tight junction complex. Metadherin is overexpressed in breast cancer tissue and breast tumor xenografts, while much lower levels are expressed in normal breast tissue. Metadherin binds to lung vasculature, one of the four common sites of breast cancer metastasis, through a C-terminal segment in the extracellular domain, blocking this lung-homing domain with antibodies or inhibiting metadherin with siRNA has been reported to inhibit breast cancer metastasis.Synonyms: 3D3/LYRIC, AEG-1, AEG1, Astrocyte elevated gene-1 protein, LYRIC, Lysine-rich CEACAM1 co-isolated protein, Metadherin, Metastasis adhesion protein
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分子量
- 64 kDa
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基因ID
- 92140
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途径
- Cellular Response to Molecule of Bacterial Origin, Cell-Cell Junction Organization
抗原
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