cDNA Sequence AF251705 (AF251705) 抗体
AF251705
适用: 人
FACS
宿主: 小鼠
Monoclonal
TX45
unconjugated
1 image
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- 抗原 See all cDNA Sequence AF251705 (AF251705) products
- cDNA Sequence AF251705 (AF251705)
- 适用
- 人
- 宿主
- 小鼠
- 克隆类型
- 单克隆
- 应用范围
- Flow Cytometry (FACS)
- 特异性
- This antibody reacts with CD300d antigen.
- 交叉反应 （详细）
- Species reactivity (tested):Human (U937, Monocytes)
- 纯化方法
- Protein A agarose
- 免疫原
- Ba/F3 transfectant expressing the human MAIR-II
- 克隆位点
- TX45
- 亚型
- IgG1
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 浓度
- 1.0 mg/mL
- 缓冲液
- PBS containing 50 % glycerol, pH 7.2. No preservative is contained.
- 储存液
- Without preservative
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- 抗原
- cDNA Sequence AF251705 (AF251705)
- 别名
- MAIR-2 (Myeloid-Associated Immunoglobulin-Like Receptor) (AF251705 产品)
- 别名
- CLM4 antibody, Cd300c antibody, Cd300d antibody, DIgR1 antibody, Igsf7 antibody, Lmir2 antibody, MAIR-II antibody, CD300C molecule 2 antibody, Cd300c2 antibody
- 背景
- Immune responses are regulated by opposing positive and negative signals triggered by the interaction of activating and inhibitory cell surface receptors with their ligands. Shibuya et al. identified novel paired activated and inhibitory immunoglobulin-like receptors, designated myeloid-associated immunoglobulin-like receptor (MAIR) I and MAIR-II, whose extracellular domains are highly conserved by each other. MAIR-I, expressed on the majority of myeloid cells, including macrophages, granulocytes, mast cells, and dendritic cells, contains the tyrosine-based sorting motif and the immunoreceptor tyrosine-based inhibitory motif-like sequences in the cytoplasmic domains. On the other hand, MAIR-II, expressed on subsets of peritoneal macrophages and B cells, associates with the immunoreceptor tyrosine-based activation motif-bearing adaptor DAP12. MAIR-I is also known as CD300a/ CMRF-35-like Ig-like molecule-8 (CLM-8)/leukocyte mono-Ig-like receptor 1 (LMIR1). MAIR-II is also known as CD300d/LMIR2/CLM-4/dendritic cell-derived Ig-like receptor 1 (DIgR1).
- 基因ID
- 140497
- NCBI登录号
- NP_598919
- UniProt
- Q7TSN2
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