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IL27 抗体 (FITC)

IL27 适用: 人 FACS 宿主: 小鼠 Monoclonal B-G49 FITC
产品编号 ABIN1107838
发货至: 中国
  • 抗原 See all IL27 抗体
    IL27 (Interleukin-27 Subunit alpha (IL27))
    适用
    • 16
    • 14
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    宿主
    • 16
    • 3
    小鼠
    克隆类型
    • 16
    • 3
    单克隆
    标记
    • 11
    • 1
    • 1
    • 1
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    This IL27 antibody is conjugated to FITC
    应用范围
    • 8
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
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    • 2
    Flow Cytometry (FACS)
    特异性
    Recognizes both natural and recombinant Human IL-27
    交叉反应 (详细)
    Species reactivity (tested):Human.
    纯化方法
    Ion Exchange Chromatography.
    免疫原
    Recombinant Human IL-27.
    克隆位点
    B-G49
    亚型
    IgG2a
    Top Product
    Discover our top product IL27 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 5 % BSA as stabilizer and 0.09 % Sodium Azide as preservative.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    Store the antibody undiluted at 2-8 °C.
  • 抗原
    IL27 (Interleukin-27 Subunit alpha (IL27))
    别名
    Interleukin-27 / IL27A (IL27 产品)
    别名
    IL-27 antibody, IL-27A antibody, IL27A antibody, IL27p28 antibody, IL30 antibody, p28 antibody, EUROIMAGE1875335 antibody, IL25 antibody, IL27 antibody, IL27w antibody, R33729_1 antibody, SF20 antibody, IL-27p28 antibody, Il30 antibody, interleukin 27 antibody, myeloid derived growth factor antibody, IL27 antibody, MYDGF antibody, Il27 antibody
    背景
    Like interleukin-23 (IL-23), IL-27 is a recently discovered member of the IL-6/IL-12 family of proinflammatory and immunoregulatory cytokines. It exists as a heterodimer composed of the p40-related protein EBI3 and an IL-12 p35-related protein termed p28. IL-27 is produced after activation by antigen-presenting cells and induces proliferation of naive but not memory CD4+ T-cells. It acts by binding to its receptor WSX-1 and gp130 which results in the activation of a Jak/STAT signaling cascade, suggesting the IL-27 is involved in the regulation of immune processes. It has been suggested that IL-27 can also be used as a therapeutic agent against cancer as it can also induce tumor-specific anti-tumor activity mediated through CD8+ T-cells, IFN-gamma, and T-bet.Synonyms: IL-27 subunit alpha, IL-30, IL27-A, IL30, Interleukin-30, p28
    基因ID
    246778
    NCBI登录号
    NP_663634
    UniProt
    Q8NEV9
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