HLA-DMA 抗体
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- 抗原 See all HLA-DMA 抗体
- HLA-DMA (Major Histocompatibility Complex, Class II, DM alpha (HLA-DMA))
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适用
- 小鼠
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宿主
- 大鼠
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克隆类型
- 单克隆
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标记
- This HLA-DMA antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Flow Cytometry (FACS), Functional Studies (Func), Immunohistochemistry (Frozen Sections) (IHC (fro))
- 特异性
- The antibody reacts with murine MHC class II glycoproteins. It recognizes a shared determinant on I-Ab, I-Ad, I-Aq, and I-Ed, I-Ek alloantigens, but it does not react with I-Af, I-Ak, I-As. This antibody can inhibit I-A-restricted T cell responses of the H-2b, H-2d, H-2q, H-2u but not H-2f, H-2k, H-2s haplotypes.
- 交叉反应 （详细）
- Species reactivity (tested):Mouse
- 纯化方法
- Protein-G affinity chromatography
- 纯度
- > 95 % pure by SDS-PAGE
- 免疫原
- Activated C57BL/6 mouse spleen cells
- 克隆位点
- M5-114
- 亚型
- IgG2b
- Top Product
- Discover our top product HLA-DMA Primary Antibody
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anti-Major Histocompatibility Complex, Class II, DM alpha (HLA-DMA) (AA 1-261) antibody
HLA-DMA 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Major Histocompatibility Complex, Class II, DM alpha (HLA-DMA) (AA 1-261) antibodyHLA-DMA 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 3F12-F11 unconjugated
anti-Major Histocompatibility Complex, Class II, DM alpha (HLA-DMA) antibodyHLA-DMA 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Major Histocompatibility Complex, Class II, DM alpha (HLA-DMA) (AA 27-233) antibodyHLA-DMA 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Major Histocompatibility Complex, Class II, DM alpha (HLA-DMA) antibodyHLA-DMA 适用: 人, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Major Histocompatibility Complex, Class II, DM alpha (HLA-DMA) (AA 58-107) antibodyHLA-DMA 适用: 人, 兔 WB 宿主: 兔 Polyclonal unconjugated
anti-Major Histocompatibility Complex, Class II, DM alpha (HLA-DMA) (AA 1-261) antibodyHLA-DMA 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 浓度
- 1.0 mg/mL
- 缓冲液
- Azide free phosphate buffered saline (PBS), approx. pH 7.4, 0.2 μm filter sterilized
- 储存液
- Azide free
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.
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- 抗原
- HLA-DMA (Major Histocompatibility Complex, Class II, DM alpha (HLA-DMA))
- Abstract
- HLA-DMA 产品
- 背景
- MHC (major histocompatibility complex) class II molecules are transmembrane glycoproteins expressed on the surface of professional antigen-presenting cells, such as macrophages, dendritic cells and B cells. Before their exposition on the cell surface, the MHC class II molecules react with endocytosed exogenous antigens, which are then presented to the T cells. The antigen-binding grove between MHC class II alpha and beta chain is open at both ends and is 15-24 amino acid residues long.Synonyms: DM alpha chain, DMA, HLA class II histocompatibility antigen, MHC class II antigen DMA, RING6, Really interesting new gene 6 protein
- 基因ID
- 3108
- NCBI登录号
- NP_006111
- UniProt
- P28067
- 途径
- Cancer Immune Checkpoints, Human Leukocyte Antigen (HLA) in Adaptive Immune Response
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