电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

HLA B7 抗体

HLA B7 适用: 人 IHC (p) 宿主: 小鼠 Monoclonal EP-4 unconjugated
产品编号 ABIN1107562
发货至: 中国
  • 抗原 See all HLA B7 抗体
    HLA B7 (HLA Class I B7 Alpha (HLA B7))
    适用
    • 13
    • 3
    • 2
    • 2
    • 2
    宿主
    • 11
    • 2
    小鼠
    克隆类型
    • 11
    • 2
    单克隆
    标记
    • 7
    • 4
    • 2
    This HLA B7 antibody is un-conjugated
    应用范围
    • 10
    • 3
    • 2
    • 1
    Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    特异性
    This antibody clone EP-4 recognizes the HLA-B27 cell surface antigen on Human cells. Since EP-4 recognizes the HLA-B27 antigen, it may be used to HLA type human lymphoctyes. Approximately 60 % of patients with ankylosing spondylitis are HLA-B27 positive. This reagent can be used to help identify this HLA haplotype in Human lymphocytes. Monoclonal antibody EP-4 recognizes the HLA-B27 antigen expressed on individuals with this HLA haplotype.
    交叉反应 (详细)
    Species reactivity (tested):Human.
    纯化方法
    Purified
    免疫原
    Native purified from lymphocytes of HLA-B27 individual.
    克隆位点
    EP-4
    亚型
    IgM
    Top Product
    Discover our top product HLA B7 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 浓度
    0.1 mg/mL
    缓冲液
    PBS, 0.05 % Sodium Azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or -20 °C for longer.
  • 抗原
    HLA B7 (HLA Class I B7 Alpha (HLA B7))
    Abstract
    HLA B7 产品
    别名
    AS antibody, HLAB antibody, SPDA1 antibody, major histocompatibility complex, class I, B antibody, HLA-B antibody
    背景
    HLA-B belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. Class I molecules play a central role in the immune system by presenting peptides derived from the endoplasmic reticulum lumen. They are expressed in nearly all cells. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon 1 encodes the leader peptide, exon 2 and 3 encode the alpha1 and alpha2 domains, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region and exons 6 and 7 encode the cytoplasmic tail. Polymorphisms within exon 2 and exon 3 are responsible for the peptide binding specificity of each class one molecule. Typing for these polymorphisms is routinely done for bone marrow and kidney transplantation. Hundreds of HLA-B alleles have been describedSynonyms: B-7 alpha chain, HLA class I histocompatibility antigen, HLAB, MHC class I antigen B7
    基因ID
    3106
    NCBI登录号
    NP_005505
    UniProt
    P01889
    途径
    Human Leukocyte Antigen (HLA) in Adaptive Immune Response
You are here:
客服