The antibody is specific for Cytomegalovirus glycoprotein B late neutralizing antigen. Reacts with MRC-5 infected cells but not uninfected cells. This antibody has been found to be Neutralizing.
Immunofluorescence. Reactive only in acetone fixed CMV infected cells or frozen sections. ELISA. Immunohistochemistry on frozen sections. Neutralization. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
限制
仅限研究用
浓度
1.0 mg/mL
缓冲液
PBS, 0.09 % Sodium Azide
储存液
Sodium azide
注意事项
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
注意事项
This product is photosensitive and should be protected from light
储存条件
4 °C
储存方法
Store the antibody undiluted at 2-8 °C DO NOT FREEZE!
抗原
CMV gB
物质类
Viral Protein
背景
Human Cytomegalovirus (HCMV) glycoprotein B (gB) is an abundant virion envelope protein that has been shown to be essential for the infectivity of HCMV. HCMV gB is also one of the most immunogenic virus-encoded proteins, and a significant fraction of virus neutralizing antibodies are directed at gB. Glycoprotein B (gB) is the main antigenic protein within the envelope of HCMV. It is required for CMV mediated membrane fusion along with the gH/gL complex. The unprocessed precursor of HCMV gB is 906 amino acids in length, wit a MW of approximately 100 kDa.Synonyms: Cytomegalovirus, Glycoprotein B, HCMV, HHV5, UL55