FGF8 抗体 (C-Term)
(1 reference)-
- 抗原 See all FGF8 抗体
- FGF8 (Fibroblast Growth Factor 8 (Androgen-Induced) (FGF8))
-
抗原表位
- C-Term
-
适用
- 人, 小鼠, 大鼠
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This FGF8 antibody is un-conjugated
-
应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 特异性
- This antibody detects FGF8 (C-term). No cross reactivity with other proteins.
- 交叉反应 （详细）
- Species reactivity (tested):Human, Mouse, Rat.
- 纯化方法
- Immunogen affinity purified
- 免疫原
- A synthetic peptide corresponding to a sequence at the C-terminal of human FGF8 .Remarks: Sequence is identical to the related rat and mouse sequence.
- 亚型
- IgG
- Top Product
- Discover our top product FGF8 Primary Antibody
-
anti-Fibroblast Growth Factor 8 (Androgen-Induced) (FGF8) (AA 65-133) antibody
FGF8 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2A10 unconjugated
anti-Fibroblast Growth Factor 8 (Androgen-Induced) (FGF8) (AA 131-233) antibodyFGF8 适用: 小鼠, 大鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Fibroblast Growth Factor 8 (Androgen-Induced) (FGF8) (AA 30-59), (N-Term) antibodyFGF8 适用: 小鼠 WB 宿主: 兔 Polyclonal RB40263 unconjugated
anti-Fibroblast Growth Factor 8 (Androgen-Induced) (FGF8) (AA 65-133) antibodyFGF8 适用: 人 ELISA, PLA 宿主: 小鼠 Monoclonal 2A11 unconjugated
anti-Fibroblast Growth Factor 8 (Androgen-Induced) (FGF8) (C-Term) antibodyFGF8 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Fibroblast Growth Factor 8 (Androgen-Induced) (FGF8) (Internal Region) antibodyFGF8 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Fibroblast Growth Factor 8 (Androgen-Induced) (FGF8) (AA 23-143) antibodyFGF8 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Fibroblast Growth Factor 8 (Androgen-Induced) (FGF8) (AA 32-66), (N-Term) antibodyFGF8 适用: 人 WB 宿主: 兔 Polyclonal RB49207 unconjugated
anti-Fibroblast Growth Factor 8 (Androgen-Induced) (FGF8) (AA 65-133) antibodyFGF8 适用: 人 ELISA 宿主: 小鼠 Monoclonal 2A12 unconjugated
anti-Fibroblast Growth Factor 8 (Androgen-Induced) (FGF8) (Internal Region) antibodyFGF8 适用: 人, 小鼠, 大鼠 WB, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
-
- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
-
- 溶解方式
- 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- 缓冲液
- 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg NaN3
- 储存液
- Sodium azide, Thimerosal (Merthiolate)
- 注意事项
- This product contains Sodium azide and Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
-
-
: "Sonic hedgehog protein regulates fibroblast growth factor 8 expression in metanephric explant culture from BALB/c mice: Possible mechanisms associated with renal morphogenesis." in: Molecular medicine reports, Vol. 14, Issue 4, pp. 2929-36, (2017) (PubMed).
-
: "Sonic hedgehog protein regulates fibroblast growth factor 8 expression in metanephric explant culture from BALB/c mice: Possible mechanisms associated with renal morphogenesis." in: Molecular medicine reports, Vol. 14, Issue 4, pp. 2929-36, (2017) (PubMed).
-
- 抗原
- FGF8 (Fibroblast Growth Factor 8 (Androgen-Induced) (FGF8))
- 别名
- FGF8 (FGF8 产品)
- 背景
- Fibroblast growth factor 8 (androgen-induced), also known as FGF8 or AIGF, is a human gene which maps to 10q24. The protein encoded by this gene are secreted proteins that interact with FGF tyrosine kinase receptors to mediate growth and development. This protein is known to be a factor that supports androgen and anchorage independent growth of mammary tumor cells. Overexpression of this gene has been shown to increase tumor growth and angiogensis. The temporal and spatial patterns of this gene expression suggest that FGF8 is involved in gastrulation, regionalization of the brain, and organogenesis of the limb and face as an embryonic epithelial factor. The adult expression of FGF8 is restricted to gonads, including testes and ovaries. FGF8 stimulated growth of human prostate carcinoma cells and mouse fibroblasts and mammary carcinoma cells in a dose-dependent manner. It also may play an important role in growth and patterning of limbs, face, and central nervous system. FGF8 is expressed in increased levels in breast cancer and in lactating human breast, it was also detected in human milk. A survey of other normal tissues showed that FGF8 is expressed in the proliferative cells of the skin and epithelial cells in colon, ovary, fallopian tube, and uterus.Synonyms: AIGF, Androgen-induced growth factor, FGF-8, Fibroblast growth factor 8, HBGF8, Heparin-binding growth factor 8
- 基因ID
- 2253
- NCBI登录号
- NP_149354
- UniProt
- P55075
- 途径
- RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Dopaminergic Neurogenesis
-
