Basal Cell Cytokeratin 抗体
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- 抗原
- Basal Cell Cytokeratin
- 适用
- 人, 兔, 大鼠, 豚鼠, 小鸡, 犬, Hamster, Pig, Quail, 斑马鱼
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- 非结合性
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应用范围
- Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (IF)
- 特异性
- Clone RCK103 is a Cytokeratin antibody recognizing (amongst others) Cytokeratin 5. This monoclonal antibody stains basal cells in combined and stratified epithelial tissues. It recognizes the stem cell population, including the so-called amplifying cells in the prostate epithelium.
- 交叉反应 (详细)
- Species reactivity (tested):Canine, Chicken, Guinea Pig, Hamster, Human, Quail, Rabbit, Rat, Swine, Zebrafish.
- 纯化方法
- Purified
- 免疫原
- A mix of cell preparations containing Human cytokeratins.
- 克隆位点
- RCK103
- 亚型
- IgG1
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 浓度
- 1.0 mg/mL
- 缓冲液
- PBS, 0.09 % Sodium Azide
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
- 储存方法
- Store the antibody undiluted (protected from light) at 2-8 °C Do Not Freeze!
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- 抗原
- Basal Cell Cytokeratin
- 别名
- Cytokeratin (Basal Cell)
- 背景
- Cytokeratins are a subfamily of intermediate filament proteins and are characterized by a remarkable biochemical diversity, represented in human epithelial tissues by at least 20 different polypeptides. They range in molecular weight between 40 kDa and 68 kDa and isoelectric pH between 4.9 - 7.8. The individual human cytokeratins are numbered 1 to 20. The various epithelia in the human body usually express cytokeratins which are not only characteristic of the type of epithelium, but also related to the degree of maturation or differentiation within an epithelium. Cytokeratin subtype expression patterns are used to an increasing extent in the distinction of different types of epithelial malignancies. The cytokeratin antibodies are not only of assistance in the differential diagnosis of tumors using immunohistochemistry on tissue sections, but are also a useful tool in cytopathology and flow cytometric assays.
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