CD19 抗体 (PE)
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- 抗原 See all CD19 抗体
- CD19 (CD19 Molecule (CD19))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This CD19 antibody is conjugated to PE
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应用范围
- Flow Cytometry (FACS)
- 特异性
- Clone HD37 is specific for CD19, it recognizes a 95 kDa transmembrane glycoprotein. Testing by flow cytometry using a 'lyse-wash' method on whole blood from healthy donors showed the following values expressed in terms of % of the total lymphocyte count: Product code: AM39014AC-N (anti-CD19 APC) n: 9 Mean % positive: 9,16 S.D.: 1,95 % CV: 21,31 ------------------------------------------ Product code: AM39014FC-N (anti-CD19 FITC) n: 9 Mean % positive: 10,80 S.D.: 2,14 % CV: 19,79 ------------------------------------------ Product code: AM39014RP-N (anti-CD19 PE) n: 9 Mean % positive: 10,57 S.D.: 2,06 % CV: 19,49 ------------------------------------------
- 纯化方法
- Affinity chromatography
- 克隆位点
- HD37
- 亚型
- IgG1
- Top Product
- Discover our top product CD19 Primary Antibody
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 缓冲液
- 0.01 M sodium phosphate, 0.15 M NaCl, pH 7.3, 0.2 % BSA, 0.09 % sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
- 储存方法
- Store the antibody undiluted at 2-8 °C. Fluorochrome labelled product is photosensitive and should be protected from light.
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- 抗原
- CD19 (CD19 Molecule (CD19))
- 别名
- CD19 (CD19 产品)
- 别名
- B4 antibody, CVID3 antibody, AW495831 antibody, CD19 antibody, CD19 molecule antibody, CD19 antigen antibody, CD19 antibody, Cd19 antibody
- 背景
- Progenitor B cells mature in bone marrow and subsequently appear as mature CD19+ B cells in blood. After contact with foreign antigens and the appropriate T cell help, they may further differentiate to specific antibody-producing plasma cells.The function of the CD19 Molecule is related to signal transfer and is involved in regulation of B cell proliferation. CD19 is considered to be a characteristic B cell marker and therefore commonly used in routine immunophenotyping. Detection of CD19 expressing cells is important in the diagnosis of leukemic precursor B cells (pre-B ALL), mature B cells (B ALL), and plasma cells. Distinction between subtypes of these (acute) leukemias can be performed using CD19 antibodies together with monoclonal antibodies to cytoplasmic or membrane Ig. A large number of B cell disorders can be effectively characterized by expression of CD19 and one or more additional antigens. One example is hairy cell leukemia (HCL), which shows specific expression of CD11c, CD19, CD20 and CD103. The combination CD103/CD19 is an important tool for diagnosis of HCL. Other valuable antibody combinations for distinction between different leukemias using CD19 antibodies are CD5/CD19 (e.g. Chronic Lymphatic Leukemia), CD10/CD19 (common ALL and pre-B ALL) and CD19/cyCD79a (Acute B cell leukemia). CD19 may also be expressed on follicular dendritic cells.Synonyms: B-cell marker, B-lymphocyte surface antigen B4, Differentiation antigen CD19, Leu-12
- 基因ID
- 930
- NCBI登录号
- NP_001171569
- UniProt
- P15391
- 途径
- Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
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