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CXCR4 抗体 (N-Term)

CXCR4 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN1105964
发货至: 中国
  • 抗原 See all CXCR4 抗体
    CXCR4 (Chemokine (C-X-C Motif) Receptor 4 (CXCR4))
    抗原表位
    • 18
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    N-Term
    适用
    • 132
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    人, 小鼠, 大鼠
    宿主
    • 113
    • 22
    • 10
    • 5
    • 1
    克隆类型
    • 121
    • 30
    多克隆
    标记
    • 97
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    This CXCR4 antibody is un-conjugated
    应用范围
    • 111
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    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    特异性
    This antibody detects CD184 / CXCR4 (N-term).
    交叉反应 (详细)
    Species reactivity (tested):Human, mouse, rat.
    纯化方法
    Immunogen affinity purified
    免疫原
    A synthetic peptide corresponding to a sequence at the N-terminal of human CXCR4 .Remarks: Sequence is different to the related rat sequence by two amino acids.
    亚型
    IgG
    Top Product
    Discover our top product CXCR4 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 溶解方式
    0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    缓冲液
    5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg NaN3
    储存液
    Sodium azide, Thimerosal (Merthiolate)
    注意事项
    This product contains Sodium azide and Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
  • 抗原
    CXCR4 (Chemokine (C-X-C Motif) Receptor 4 (CXCR4))
    别名
    CD184 / CXCR4 (CXCR4 产品)
    背景
    CXCR4 is the receptor for the CXC chemokine SDF1 that has essential functions on embryo organogenesis, immunological functions and T lymphocyte trafficking. CXCR4 is the only SDF1 receptor identified so far. This suggests that CXCR4 expression is critical for the biological effects of SDF1. CXCR4 is a seven-transmembrane-spanning, G-protein-coupled receptor for the CXC chemokine PBSF/SDF-1, it functions as a co-receptor for T-cell-line tropic human immunodeficiency virus HIV-1. Tachibana et al. (1998) conclude that PBSF/SDF-1 and CXCR4 define a new signalling system for organ vascularization.Synonyms: C-X-C chemokine receptor type 4, CXC-R4, CXCR-4, FB22, Fusin, HM89, LCR1, LESTR, Leukocyte-derived seven transmembrane domain receptor, NPYRL, SDF1 receptor, Stromal cell-derived factor 1 receptor
    基因ID
    7852
    NCBI登录号
    NP_001008540
    UniProt
    P61073
    途径
    Regulation of Cell Size, CXCR4-mediated Signaling Events
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