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ITGAL 抗体

ITGAL 适用: 人 FACS, IF, IHC (fro) 宿主: 小鼠 Monoclonal DF1524 unconjugated
产品编号 ABIN1105766
发货至: 中国
  • 抗原 See all ITGAL 抗体
    ITGAL (Integrin alpha-L (ITGAL))
    适用
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    宿主
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    小鼠
    克隆类型
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    单克隆
    标记
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    This ITGAL antibody is un-conjugated
    应用范围
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    Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro))
    特异性
    This antibody specifically detects CD11a positive leucocytes. CD11a antigens are expressed on lymphocytes, granulocytes, monocytes and macrophages with increased levels on memory T cells (1,2). Clone DF1524 was clustered at the Leucovyte Typing Workshop IV (5).
    纯化方法
    Affinity chromatography
    克隆位点
    DF1524
    亚型
    IgG2b
    Top Product
    Discover our top product ITGAL Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 浓度
    0.1 mg / ml
    缓冲液
    0.01 M sodium phosphate, 0.15 M NaCl, pH 7.3, 0.2 % BSA, 0.09 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    Store the antibody undiluted at 2-8 °C.
  • 抗原
    ITGAL (Integrin alpha-L (ITGAL))
    别名
    CD11a / ITGAL (ITGAL 产品)
    别名
    CD11A antibody, LFA-1 antibody, LFA1A antibody, (p180) antibody, Cd11a antibody, LFA-1A antibody, Ly-15 antibody, Ly-21 antibody, CD11a antibody, ITGAL antibody, integrin subunit alpha L antibody, integrin alpha L antibody, ITGAL antibody, Itgal antibody
    背景
    CD11a/CD18 was first described as an accessory molecule in cytotoxic lymphocyte killing. CD11a (Integrin alpha-L) combines with CD18 (Integrin beta-2) to form the integrin LFA-1. LFA-1 mediates adhesion of lymphoid cells to the vascular endothelium in association with its ligands. The avidity of CD11a to its ligands is transiently upregulated on T cells upon activation (3). CD11a has also been shown to bind bacterial lipopolysaccarides (4).Synonyms: CD11 antigen-like family member A, Integrin alpha-L, LFA-1, LFA1, Leukocyte adhesion glycoprotein LFA-1 alpha chain, Leukocyte function-associated molecule 1 alpha chain
    基因ID
    3683
    NCBI登录号
    NP_002200
    UniProt
    P20701
    途径
    Activated T Cell Proliferation, Integrin Complex
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