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Caspase 2 抗体 (C-Term)
CASP2
适用: 人, 小鼠, 大鼠
WB, IHC (p)
宿主: 兔
Polyclonal
unconjugated
Caspase 2抗体详情
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抗原
See all Caspase 2 (CASP2) 抗体
Caspase 2 (CASP2)
(Caspase 2, Apoptosis-Related Cysteine Peptidase (CASP2))
抗原表位
All epitopes for Caspase 2 抗体
C-Term
适用
All reactivities for Caspase 2 抗体
人, 小鼠, 大鼠
宿主
All hosts for Caspase 2 抗体
兔
克隆类型
All clonalities for Caspase 2 抗体
多克隆
标记
All conjugates for Caspase 2 抗体
This Caspase 2 antibody is un-conjugated
应用范围
All applications for Caspase 2 抗体
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
特异性
This antibody detects Caspase-2 (C-term). No cross reactivity with other proteins.
交叉反应 (详细)
Species reactivity (expected):Mouse. Species reactivity (tested):Human, Rat.
纯化方法
Immunoaffinity Chromatography
免疫原
Synthetic peptide mapping at the C-terminal of Human Caspase 2 .Remarks: Sequence is identical to the related Rat and Mouse sequence.
亚型
IgG
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Discover our top product CASP2 Primary Antibody
Alternatives
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使用细节
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应用备注
Optimal working dilution should be determined by the investigator.
限制
仅限研究用
贮存及处理
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溶解方式
0.2 mL of distilled water will yield a concentration of 500 μg/mL.
缓冲液
0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium Azide, 5 mg BSA
储存液
Thimerosal (Merthiolate)
注意事项
This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
注意事项
Avoid repeated freezing and thawing.
储存条件
4 °C/-20 °C
储存方法
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Caspase 2目标详情
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抗原
Caspase 2 (CASP2)
(Caspase 2, Apoptosis-Related Cysteine Peptidase (CASP2))
别名
Caspase-2 (CASP2 产品 )
别名
xCaspase-2 antibody, Caspase-2 antibody, ICH-1 antibody, Nedd2 antibody, CASP-2 antibody, ICH1 antibody, NEDD-2 antibody, NEDD2 antibody, PPP1R57 antibody, ICH-1L/1S antibody, ICH1L1S antibody, caspase 2 antibody, caspase 2 L homeolog antibody, caspase-2 antibody, CASP2 antibody, casp2.L antibody, CpipJ_CPIJ008254 antibody, Casp2 antibody
背景
Caspase-2, which is involved in stress-induced apoptosis, is recruited into a large protein complex, the molecular composition of which remains elusive. activation of caspase-2 occurs in a complex that contains the death domain-containing protein PIDD, whose expression is induced by p53, and the adaptor protein RAIDD. Increased PIDD expression resulted in spontaneous activation of caspase-2 and sensitization to apoptosis by genotoxic stimuli. Caspase-2 acts both as a positive and negative cell death effector, depending upon cell lineage and stage of development.Synonyms: CASP-2, CASP2, ICH-1 protease, ICH1, NEDD2, Neural precursor cell expressed developmentally down-regulated protein 2
基因ID
835
NCBI登录号
NP_116764
UniProt
P42575
途径
Apoptosis , Caspase Cascade in Apoptosis , Neurotrophin Signaling Pathway
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