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Carboxy Methyl Lysine 抗体

CML EIA, WB, IHC (fro), IF, IHC (p) 宿主: 小鼠 Monoclonal CML26 unconjugated
产品编号 ABIN1105660
发货至: 中国
  • 抗原 See all Carboxy Methyl Lysine (CML) 抗体
    Carboxy Methyl Lysine (CML)
    宿主
    • 1
    • 1
    小鼠
    克隆类型
    • 1
    • 1
    单克隆
    标记
    • 2
    This Carboxy Methyl Lysine antibody is un-conjugated
    应用范围
    Enzyme Immunoassay (EIA), Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    交叉反应 (详细)
    Species reactivity (tested):Human, Multispecies cross reactant.
    纯化方法
    Protein G Chromatography
    免疫原
    Carboxy Methyl Lysine (CML)-KLH
    克隆位点
    CML26
    亚型
    IgG1
    Top Product
    Discover our top product CML Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 浓度
    0.1 mg/mL
    缓冲液
    PBS, 0.02 % Sodium Azide, 0.1 % BSA
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    Store undiluted at 2-8 °C.
  • 抗原
    Carboxy Methyl Lysine (CML)
    别名
    Carboxy Methyl Lysine (CML 产品)
    别名
    ALL antibody, BCR1 antibody, CML antibody, D22S11 antibody, D22S662 antibody, PHL antibody, BCR, RhoGEF and GTPase activating protein antibody, BCR antibody
    物质类
    Amino Acid
    背景
    CML is known to be formed from the oxidation of both carbohydrates and lipids. This makes CML a biomarker of general oxidative stress. Carboxymethyl-lysine (CML) is a well-characterized glycoxidation product that accumulates in tissues with age, and its rate of accumulation is accelerated in diabetes. Glycoxidation products are a subset of advanced glycation endproducts (AGEs) that are formed by the nonenzymatic glycation and subsequent irreversible oxidation of proteins. Oxidative stress and protein modification have been implicated in the pathogenesis of the chronic complications of diabetes, including nephropathy and atherosclerosis. The accumulation of CML in long-lived tissue such as skin collagen reflects oxidative stress over an extended period of the life-span, and has been shown to be greater in patients with diabetic complications than those without complications.Synonyms: CML, Carboxymethyl-lysine
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