Carboxy Methyl Lysine 抗体
This anti-Carboxy Methyl Lysine antibody is a 小鼠 单克隆 antibody detecting Carboxy Methyl Lysine in EIA, WB, IHC (fro), IF 和 IHC (p). Suitable for .
Quick Overview for Carboxy Methyl Lysine 抗体 (ABIN1105660)
抗原
See all Carboxy Methyl Lysine (CML) 抗体
Carboxy Methyl Lysine (CML)
宿主
小鼠
克隆类型
单克隆
标记
This Carboxy Methyl Lysine antibody is un-conjugated
应用范围
Enzyme Immunoassay (EIA), Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
克隆位点
CML26
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交叉反应 （详细）
- Species reactivity (tested):Human, Multispecies cross reactant.
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纯化方法
- Protein G Chromatography
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免疫原
- Carboxy Methyl Lysine (CML)-KLH
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亚型
- IgG1
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 0.1 mg/mL
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缓冲液
- PBS, 0.02 % Sodium Azide, 0.1 % BSA
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Store undiluted at 2-8 °C.
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- Carboxy Methyl Lysine (CML)
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别名
- Carboxy Methyl Lysine
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物质类
- Amino Acid
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背景
- CML is known to be formed from the oxidation of both carbohydrates and lipids. This makes CML a biomarker of general oxidative stress. Carboxymethyl-lysine (CML) is a well-characterized glycoxidation product that accumulates in tissues with age, and its rate of accumulation is accelerated in diabetes. Glycoxidation products are a subset of advanced glycation endproducts (AGEs) that are formed by the nonenzymatic glycation and subsequent irreversible oxidation of proteins. Oxidative stress and protein modification have been implicated in the pathogenesis of the chronic complications of diabetes, including nephropathy and atherosclerosis. The accumulation of CML in long-lived tissue such as skin collagen reflects oxidative stress over an extended period of the life-span, and has been shown to be greater in patients with diabetic complications than those without complications.Synonyms: CML, Carboxymethyl-lysine
抗原
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