This antibody detects Cadherin-2 (701-714). No cross reactivity with other proteins.
交叉反应 (详细)
Species reactivity (tested):Human, rat
纯化方法
Immunogen affinity purified
免疫原
Synthetic peptide corresponding to a sequence at the middle region of human N-Cadherin (701-714aa) .Remarks: Sequence is identical to the rat sequence.
N-cadherin (NCAD) is a member of the cadherin cell-cell adhesion receptor family that includes P-, E-,and R-cadherin and liver cell adhesion molecule (L-CAM). N-Cadherin, also known as Cadherin-2, encodes a 907-amino acid protein that includes a 159-amino acid signal sequence. Human and mouse nucleotide sequences are 96 % identical. Mouse Ncad gene consists of 16 exons dispersed over more than 200 kb of genomic DNA. Human N-cadherin gene contains 16 exons and its sequence is highly similar to both the mouse NCAD gene (including the large first and second introns) and other cadherin genes. N-cadherin is mapped to 18q11.2. Cadherin regulates dendritic spine morphogenesisSynonyms: CDH2, CDHN, CDw325, Cadherin N, N-Cadherin, NCAD, Neural cadherin