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beta Amyloid 抗体 (N-Term)

Abeta 适用: 人, 小鼠 WB, IHC (p) 宿主: 小鼠 Monoclonal 2C8 unconjugated
产品编号 ABIN1105360
发货至: 中国
  • 抗原 See all beta Amyloid (Abeta) 抗体
    beta Amyloid (Abeta) (Amyloid beta (Abeta))
    抗原表位
    • 19
    • 14
    • 11
    • 6
    • 5
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-16, N-Term
    适用
    • 68
    • 20
    • 15
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    人, 小鼠
    宿主
    • 41
    • 27
    • 2
    • 1
    小鼠
    克隆类型
    • 38
    • 28
    • 1
    单克隆
    标记
    • 61
    • 5
    • 2
    • 1
    • 1
    • 1
    This beta Amyloid antibody is un-conjugated
    应用范围
    • 50
    • 47
    • 30
    • 19
    • 14
    • 12
    • 9
    • 5
    • 5
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    交叉反应 (详细)
    Species reactivity (tested):Human, weakly with mouse brain
    纯化方法
    Protein-A Sepharose
    免疫原
    Synthetic amyloid beta peptide corresponding to amino acids 1-16 of human amyloid beta
    克隆位点
    2C8
    亚型
    IgG2b
    Top Product
    Discover our top product Abeta Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    PBS containing 50 % glycerol, pH 7.2, without preservatives
    储存液
    Without preservative
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    -20 °C
    储存方法
    Store (in aliquots) at -20 °C.
  • 抗原
    beta Amyloid (Abeta) (Amyloid beta (Abeta))
    别名
    Amyloid beta (Abeta 产品)
    别名
    AAA antibody, ABETA antibody, ABPP antibody, AD1 antibody, APPI antibody, CTFgamma antibody, CVAP antibody, PN-II antibody, PN2 antibody, aaa antibody, abeta antibody, abpp antibody, ad1 antibody, appi antibody, ctfgamma antibody, cvap antibody, pn2 antibody, Abeta antibody, Abpp antibody, Adap antibody, Ag antibody, Cvap antibody, E030013M08Rik antibody, betaApp antibody, amyloid beta precursor protein antibody, amyloid beta (A4) precursor protein antibody, APP antibody, app antibody, App antibody
    背景
    Alzheimer's disease (AD) is the most common form of dementia in the elderly. The neuropathological hallmarks are neurofibrillary tangles and senile plaques. The major protein component of the plaques is a 39-42 amino acid peptide (ß-amyloid/Aß). Aß occurs in two predominant forms with different COOH-termini, Aß 40 and Aß 42, and overproduction of Aß 42 has been suggested to be the cause of familial early-onset AD. Aß generation depends on proteolytic cleavage of the amyloid precursor protein (APP) by two unknown proteases: ß-secretase and gamma-secretase. Recent study suggested that a transmembrane aspartic protease, termed beta-site APP-cleaving enzyme (BACE), functionally acts as the ß-secretase. This antibody recognizes N-terminal of Aß 40 and Aß 42 specifically.Synonyms: Amyloid beta peptide
    途径
    Inflammasome
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