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beta Amyloid 抗体 (C-Term)

Abeta 适用: 人, 小鼠, 大鼠, 灵长类 WB, EIA, ELISA (Detection) 宿主: 小鼠 Monoclonal CA9 10C11 unconjugated
产品编号 ABIN1105357
发货至: 中国
  • 抗原 See all beta Amyloid (Abeta) 抗体
    beta Amyloid (Abeta) (Amyloid beta (Abeta))
    抗原表位
    • 18
    • 15
    • 11
    • 6
    • 5
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    • 69
    • 21
    • 14
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠, 灵长类
    宿主
    • 41
    • 28
    • 2
    • 1
    小鼠
    克隆类型
    • 38
    • 29
    • 1
    单克隆
    标记
    • 62
    • 5
    • 2
    • 1
    • 1
    • 1
    This beta Amyloid antibody is un-conjugated
    应用范围
    • 51
    • 48
    • 31
    • 19
    • 14
    • 13
    • 8
    • 5
    • 5
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA), ELISA (Detection)
    序列
    MVGGVVIA
    特异性
    This antibody specifically recognizes the C-terminal sequence of beta amyloid peptide 42 and full length beta amyloid peptide 42. The antibody does not cross react with beta amyloid peptide 40 in dot blotting and ELISA. Cross-reactivity to beta amyloid peptide 43 is less than 1 % in ELISA.
    交叉反应 (详细)
    Species reactivity (tested):Human, Primates, Mouse, Rat.
    纯化方法
    Protein G affinity purified
    免疫原
    KLH conjugated to a short peptide corresponding to the C-terminal sequence of beta amyloid peptide 42
    克隆位点
    CA9 10C11
    亚型
    IgG2b
    Top Product
    Discover our top product Abeta Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 溶解方式
    Restore with Double distillated water is recommended and to adjust the final concentration to 1.0 mg/mL.
    缓冲液
    0.01 M PBS pH 7.2
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    -20 °C
    储存方法
    Store at -20 °C.
  • 抗原
    beta Amyloid (Abeta) (Amyloid beta (Abeta))
    别名
    Amyloid beta (Abeta 产品)
    别名
    AAA antibody, ABETA antibody, ABPP antibody, AD1 antibody, APPI antibody, CTFgamma antibody, CVAP antibody, PN-II antibody, PN2 antibody, aaa antibody, abeta antibody, abpp antibody, ad1 antibody, appi antibody, ctfgamma antibody, cvap antibody, pn2 antibody, Abeta antibody, Abpp antibody, Adap antibody, Ag antibody, Cvap antibody, E030013M08Rik antibody, betaApp antibody, amyloid beta precursor protein antibody, amyloid beta (A4) precursor protein antibody, APP antibody, app antibody, App antibody
    背景
    Amyloid beta peptide 42 (Aβ42) is best known for its role in the formation of senile plaques in the brain of patients with Alzheimer's disease. Aβ42 and Aβ40 are the two major amyloid peptides that are produced after cleavage of amyloid precursor protein by secretases. Aβ42 (42 amino acids) is very fibrillogenic. The beta pleated structure of Aβ42 constituents the initial and key component of the insoluble amyloid fibril in senile plaque. It is widely accepted that Aβ42 contributes to the pathogenesis of Alzheimer's disease. One proposition is that the deposition of amyloid fibril onto the brain tissue results in Alzheimer's disease. Another is that the neurotoxicity of Aβ42 oligomer is the cause of the disease.
    基因ID
    351
    途径
    Inflammasome
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