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ACIN1 抗体 (N-Term)

ACIN1 适用: 人 WB, IP 宿主: 小鼠 Monoclonal 3H8 unconjugated
产品编号 ABIN1105223
发货至: 中国
  • 抗原 See all ACIN1 抗体
    ACIN1 (Apoptotic Chromatin Condensation Inducer 1 (ACIN1))
    抗原表位
    • 9
    • 7
    • 7
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-523, N-Term
    适用
    • 41
    • 22
    • 13
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    宿主
    • 38
    • 4
    小鼠
    克隆类型
    • 38
    • 4
    单克隆
    标记
    • 35
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ACIN1 antibody is un-conjugated
    应用范围
    • 33
    • 20
    • 10
    • 8
    • 6
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunoprecipitation (IP)
    特异性
    This antibody reacts withAcinusL.
    交叉反应 (详细)
    Species reactivity (tested):Human.
    Does not react with mouse (WR19L, NIH3T3) or hamster (CHO).
    纯化方法
    Protein A agarose beads
    免疫原
    GST-human AcinusL fusion protein corresponding to N-terminal amino acids (1~523 a.a.)
    克隆位点
    3H8
    亚型
    IgG1
    Top Product
    Discover our top product ACIN1 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    PBS containing 50 % glycerol, pH 7.2. Contains no preservatives.
    储存液
    Without preservative
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    -20 °C
    储存方法
    Store (in aliquots) at -20 °C.
  • 抗原
    ACIN1 (Apoptotic Chromatin Condensation Inducer 1 (ACIN1))
    别名
    Acinus / ACIN1 (ACIN1 产品)
    别名
    acinus antibody, acinusb antibody, fi14c05 antibody, wu:fe06a10 antibody, wu:fi14c05 antibody, acinusa antibody, acinusl antibody, ik:tdsubc_2g5 antibody, si:zc14a17.12 antibody, wu:fb04g06 antibody, wu:fb40f03 antibody, wu:fb68h03 antibody, wu:fb80f07 antibody, wu:fc12e10 antibody, xx:tdsubc_2g5 antibody, acn antibody, ACINUS antibody, ACN antibody, fSAP152 antibody, 2610036I19Rik antibody, 2610510L13Rik antibody, Acinus antibody, Acn antibody, C79325 antibody, acinusL antibody, acinusS antibody, mKIAA0670 antibody, apoptotic chromatin condensation inducer 1b antibody, apoptotic chromatin condensation inducer 1a antibody, apoptotic chromatin condensation inducer 1 antibody, apoptotic chromatin condensation inducer 1 S homeolog antibody, acin1b antibody, acin1a antibody, acin1 antibody, ACIN1 antibody, acin1.S antibody, Acin1 antibody
    背景
    Chromatin condensation and nuclear fragmentation (CCNF) are hallmarks of apoptosis. CCNF is triggered by the activation of members of the caspase family, caspase-activated DNase (CAD/DFF40) and several novel proteins including AIF and CIDE. A new inducer of chromatin condensation was recently identified and designated Acinus (Apoptotic Chromatin Condensation Inducer in the Nucleus). The 220 kDa Acinus protein is cleaved by caspase-3 and an additional unknown protease to generate a 17 kDa peptide that which causes chromatin condensation in vitro when added to purified nuclei. Acinus also induces apoptotic chromatin condensation in cells. Three different spliced forms of Acinus have been identified in human and mouse and designated AcinusL, AcinusS, and AcinusS'. Acinus is ubiquitously expressed.Synonyms: Apoptotic chromatin condensation inducer in the nucleus, KIAA0670
    分子量
    220 kDa
    基因ID
    22985
    NCBI登录号
    NP_001158286
    UniProt
    Q9UKV3
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