Prosaposin 抗体 (AA 325-524)
(2 references)-
- 抗原 See all Prosaposin (PSAP) 抗体
- Prosaposin (PSAP)
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抗原表位
- AA 325-524
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This Prosaposin antibody is un-conjugated
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应用范围
- Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS), Immunocytochemistry (ICC)
- 原理
- PSAP Antibody
- 纯化方法
- Purified antibody
- 免疫原
- Purified recombinant fragment of human PSAP (AA: 325-524 ) expressed in E. Coli.
- 克隆位点
- 4D5F4
- 亚型
- IgG1
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anti-Prosaposin (PSAP) (AA 17-524) antibody
PSAP 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Prosaposin (PSAP) (AA 60-310) antibodyPSAP 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Prosaposin (PSAP) (AA 17-216) antibodyPSAP 适用: 人 WB, IHC, ELISA, FACS, ICC 宿主: 小鼠 Monoclonal 3B4A8 unconjugated
anti-Prosaposin (PSAP) (AA 18-524) antibodyPSAP 适用: 人 WB, ELISA, IHC (p), IP 宿主: 小鼠 Monoclonal 1D1-C12 unconjugated
anti-Prosaposin (PSAP) (AA 325-524) antibodyPSAP 适用: 人 WB, IHC, ELISA, FACS, IF/ICC 宿主: 小鼠 Monoclonal unconjugated
anti-Prosaposin (PSAP) (AA 311-391) antibodyPSAP 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Prosaposin (PSAP) (Internal Region) antibodyPSAP 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Prosaposin (PSAP) (AA 1-524) antibodyPSAP 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2F6 unconjugated
anti-Prosaposin (PSAP) antibodyPSAP 适用: 人 IHC 宿主: 小鼠 Monoclonal MSVA-452M unconjugated Recombinant Antibody
anti-Prosaposin (PSAP) (AA 1-524) antibodyPSAP 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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ELISA: 1/10000
FCM: 1/200 - 1/400
ICC: 1/50 - 1/500
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified antibody in PBS with 0.05 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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: "The interaction of the second Kunitz-type domain (KD2) of TFPI-2 with a novel interaction partner, prosaposin, mediates the inhibition of the invasion and migration of human fibrosarcoma cells." in: The Biochemical journal, Vol. 441, Issue 2, pp. 665-74, (2011) (PubMed).
: "Prosaposin down-modulation decreases metastatic prostate cancer cell adhesion, migration, and invasion." in: Molecular cancer, Vol. 9, pp. 30, (2010) (PubMed).
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: "The interaction of the second Kunitz-type domain (KD2) of TFPI-2 with a novel interaction partner, prosaposin, mediates the inhibition of the invasion and migration of human fibrosarcoma cells." in: The Biochemical journal, Vol. 441, Issue 2, pp. 665-74, (2011) (PubMed).
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- 抗原
- Prosaposin (PSAP)
- 别名
- PSAP (PSAP 产品)
- 别名
- GLBA antibody, SAP1 antibody, AI037048 antibody, SGP-1 antibody, SGP1A antibody, cb759 antibody, wu:fa14a06 antibody, wu:fb36e02 antibody, wu:fb58g07 antibody, PSAP antibody, PSP-A antibody, SFTPA1B antibody, SP-A antibody, prosaposin antibody, surfactant protein A1 antibody, PSAP antibody, Psap antibody, psap antibody, LOC100011417 antibody, LOC100304726 antibody, LOC100526719 antibody, SFTPA1 antibody
- 背景
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Description: This gene encodes a highly conserved glycoprotein which is a precursor for 4 cleavage products: saposins A, B, C, and D. Each domain of the precursor protein is approximately 80 amino acid residues long with nearly identical placement of cysteine residues and glycosylation sites. Saposins A-D localize primarily to the lysosomal compartment where they facilitate the catabolism of glycosphingolipids with short oligosaccharide groups. The precursor protein exists both as a secretory protein and as an integral membrane protein and has neurotrophic activities. Mutations in this gene have been associated with Gaucher disease, Tay-Sachs disease, and metachromatic leukodystrophy. Alternative splicing results in multiple transcript variants encoding different isoforms.
Aliases: GLBA, SAP1
- 分子量
- 58.1kDa
- 基因ID
- 5660
- HGNC
- 5660
- UniProt
- P07602
- 途径
- Positive Regulation of Endopeptidase Activity
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