Surfactant Protein C 抗体 (AA 60-180)
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- 抗原 See all Surfactant Protein C (SFTPC) 抗体
- Surfactant Protein C (SFTPC)
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抗原表位
- AA 60-180
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This Surfactant Protein C antibody is un-conjugated
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应用范围
- ELISA
- 原理
- SFTPC Antibody
- 纯化方法
- Purified antibody
- 免疫原
- Purified recombinant fragment of human SFTPC (AA: 60-180 ) expressed in E. Coli.
- 克隆位点
- 5E6A9
- 亚型
- IgG1
- Top Product
- Discover our top product SFTPC Primary Antibody
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- 应用备注
- ELISA: 1/10000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified antibody in PBS with 0.05 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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Role of endoplasmic reticulum stress in epithelial-mesenchymal transition of alveolar epithelial cells: effects of misfolded surfactant protein." in: American journal of respiratory cell and molecular biology, Vol. 45, Issue 3, pp. 498-509, (2011) (PubMed).
: "Meckel-Gruber syndrome protein MKS3 is required for endoplasmic reticulum-associated degradation of surfactant protein C." in: The Journal of biological chemistry, Vol. 284, Issue 48, pp. 33377-83, (2009) (PubMed).
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Role of endoplasmic reticulum stress in epithelial-mesenchymal transition of alveolar epithelial cells: effects of misfolded surfactant protein." in: American journal of respiratory cell and molecular biology, Vol. 45, Issue 3, pp. 498-509, (2011) (PubMed).
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- 抗原
- Surfactant Protein C (SFTPC)
- 别名
- SFTPC (SFTPC 产品)
- 别名
- SFTPC antibody, SPC antibody, SP-C antibody, psp-c antibody, sftp2 antibody, xSP-C antibody, Bricd6 antibody, SP5 antibody, Sftp-2 antibody, Sftp2 antibody, pro-SpC antibody, BRICD6 antibody, PSP-C antibody, SFTP2 antibody, SMDP2 antibody, surfactant protein C antibody, surfactant, pulmonary-associated protein C S homeolog antibody, surfactant, pulmonary-associated protein C antibody, surfactant associated protein C antibody, SFTPC antibody, sftpc.S antibody, sftpc antibody, Sftpc antibody
- 背景
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Description: This gene encodes the pulmonary-associated surfactant protein C (SPC), an extremely hydrophobic surfactant protein essential for lung function and homeostasis after birth. Pulmonary surfactant is a surface-active lipoprotein complex composed of 90 % lipids and 10 % proteins which include plasma proteins and apolipoproteins SPA, SPB, SPC and SPD. The surfactant is secreted by the alveolar cells of the lung and maintains the stability of pulmonary tissue by reducing the surface tension of fluids that coat the lung. Multiple mutations in this gene have been identified, which cause pulmonary surfactant metabolism dysfunction type 2, also called pulmonary alveolar proteinosis due to surfactant protein C deficiency, and are associated with interstitial lung disease in older infants, children, and adults. Alternatively spliced transcript variants encoding different protein isoforms have been identified.
Aliases: SP-C, PSP-C, SFTP2, SMDP2
- 分子量
- 21kDa
- 基因ID
- 6440
- HGNC
- 6440
- UniProt
- P11686
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