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NEFH 抗体 (AA 968-1020)

NEFH 适用: 人 IHC, ELISA 宿主: 小鼠 Monoclonal 8H10 unconjugated
产品编号 ABIN1098127
发货至: 中国
  • 抗原 See all NEFH 抗体
    NEFH (Neurofilament, Heavy Polypeptide (NEFH))
    抗原表位
    • 16
    • 8
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 968-1020
    适用
    • 112
    • 83
    • 64
    • 50
    • 31
    • 23
    • 12
    • 12
    • 9
    • 9
    • 9
    • 7
    • 7
    • 5
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    宿主
    • 67
    • 56
    • 8
    小鼠
    克隆类型
    • 81
    • 50
    单克隆
    标记
    • 82
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This NEFH antibody is un-conjugated
    应用范围
    • 81
    • 39
    • 37
    • 26
    • 25
    • 24
    • 19
    • 14
    • 13
    • 13
    • 12
    • 9
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Immunohistochemistry (IHC), ELISA
    原理
    NEFH Antibody
    纯化方法
    Purified antibody
    免疫原
    Purified recombinant fragment of human NEFH (AA: 968-1020) expressed in E. Coli.
    克隆位点
    8H10
    亚型
    IgG1
    Top Product
    Discover our top product NEFH Primary Antibody
  • 应用备注
    ELISA: 1/10000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified antibody in PBS with 0.05 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Singh, Yan, Hull, Read, OSullivan, Henderson, Rose, Greer, McCombe: "Levels of phosphorylated axonal neurofilament subunit H (pNfH) are increased in acute ischemic stroke." in: Journal of the neurological sciences, Vol. 304, Issue 1-2, pp. 117-21, (2011) (PubMed).

    Sellner, Patel, Dassan, Brown, Petzold: "Hyperacute detection of neurofilament heavy chain in serum following stroke: a transient sign." in: Neurochemical research, Vol. 36, Issue 12, pp. 2287-91, (2011) (PubMed).

  • 抗原
    NEFH (Neurofilament, Heavy Polypeptide (NEFH))
    别名
    NEFH (NEFH 产品)
    别名
    NF-H antibody, NF200 antibody, Nfh antibody, mKIAA0845 antibody, NFH antibody, NEFH antibody, neurofilament heavy polypeptide antibody, neurofilament, heavy polypeptide antibody, neurofilament heavy antibody, MCYG_06231 antibody, Nefh antibody, NEFH antibody
    背景

    Description: Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and functionally maintain neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the heavy neurofilament protein. This protein is commonly used as a biomarker of neuronal damage and susceptibility to amyotrophic lateral sclerosis (ALS) has been associated with mutations in this gene.

    Aliases: NFH

    分子量
    112.4kDa
    基因ID
    4744
    HGNC
    4744
    UniProt
    P12036
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