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CSNK2A2 抗体 (AA 194-350)

CSNK2A2 适用: 人 WB, ELISA, FACS 宿主: 小鼠 Monoclonal 1E1 unconjugated
产品编号 ABIN1098114
发货至: 中国
  • 抗原 See all CSNK2A2 抗体
    CSNK2A2 (Casein Kinase 2, alpha Prime Polypeptide (CSNK2A2))
    抗原表位
    • 8
    • 7
    • 6
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 194-350
    适用
    • 44
    • 22
    • 12
    • 5
    • 5
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    宿主
    • 42
    • 2
    小鼠
    克隆类型
    • 41
    • 3
    单克隆
    标记
    • 20
    • 5
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CSNK2A2 antibody is un-conjugated
    应用范围
    • 30
    • 26
    • 10
    • 7
    • 5
    • 2
    • 1
    Western Blotting (WB), ELISA, Flow Cytometry (FACS)
    原理
    CSNK2A2 Antibody
    纯化方法
    Ascitic fluid
    免疫原
    Purified recombinant fragment of human CSNK2A2 (AA: 194-350) expressed in E. Coli.
    克隆位点
    1E1
    亚型
    IgG1
  • 应用备注

    ELISA: 1/10000

    FCM: 1/200 - 1/400

    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Ascitic fluid containing 0.03 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Chemnitz, Pieper, Grüttner, Hauber: "Phosphorylation of the HuR ligand APRIL by casein kinase 2 regulates CD83 expression." in: European journal of immunology, Vol. 39, Issue 1, pp. 267-79, (2009) (PubMed).

    Schäfer, Götz, Dudek, Hessenauer, Matti, Montenarh: "KIF5C: a new binding partner for protein kinase CK2 with a preference for the CK2alpha' subunit." in: Cellular and molecular life sciences : CMLS, Vol. 66, Issue 2, pp. 339-49, (2009) (PubMed).

  • 抗原
    CSNK2A2 (Casein Kinase 2, alpha Prime Polypeptide (CSNK2A2))
    别名
    CSNK2A2 (CSNK2A2 产品)
    别名
    CK2A2 antibody, CSNK2A1 antibody, 1110035J23Rik antibody, C77789 antibody, CK2 antibody, CSNK2A2 antibody, ck2a2 antibody, csnk2a1 antibody, wu:fi09h12 antibody, casein kinase 2 alpha 2 antibody, casein kinase 2, alpha prime polypeptide antibody, casein kinase 2 alpha 2 L homeolog antibody, casein kinase 2, alpha prime polypeptide a antibody, CSNK2A2 antibody, Csnk2a2 antibody, csnk2a2.L antibody, csnk2a2 antibody, csnk2a2a antibody
    背景

    Description: Casein kinase II (CK2) is a constitutively active, ubiquitously expressed serine/threonine protein kinase that is thought to have a regulatory function in cell proliferation, cell differentiation and apoptosis. CK2 functions as a tetrameric complex consisting of two regulatory beta-subunits and two catalytic units (alpha and alpha') in a homomeric or heteromeric conformation. Whilst the alpha- and alpha'-subunits are catalytically identical, proteins that regulate CK2, such as cdc2 and Hsp90, preferentially bind to the alpha and not the alpha'-subunit. CK2 can phosphorylate a number of key intracellular signaling proteins implicated in tumor suppression (p53 and PTEN) and tumorigenesis (myc, jun, NF-kappaB). CK2 is also thought to influence Wnt signaling via beta-catenin phosphorylation and the PI 3-K signaling pathway via the phosphorylation of Akt.

    Aliases: CK2A2, CSNK2A1, FLJ43934

    分子量
    41.2kDa
    基因ID
    1459
    HGNC
    1459
    UniProt
    P19784
    途径
    SARS-CoV-2 Protein Interactome
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