SRY 抗体 (AA 1-204)
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- 抗原 See all SRY 抗体
- SRY (Sex Determining Region Y (SRY))
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抗原表位
- AA 1-204
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This SRY antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS)
- 纯化方法
- purified
- 免疫原
- Purified recombinant fragment of human SRY (AA:1-204) expressed in E. coli.
- 克隆位点
- 1G4
- 亚型
- IgG1
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- 应用备注
- ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000, FCM: 1:200 - 1:400
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified antibody in PBS with 0.05 % sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- 4°C, -20°C for long term storage
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Epigenetic gene silencing by the SRY protein is mediated by a KRAB-O protein that recruits the KAP1 co-repressor machinery." in: The Journal of biological chemistry, Vol. 284, Issue 51, pp. 35670-80, (2009) (PubMed).
: "Regulation of monoamine oxidase A by the SRY gene on the Y chromosome." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 23, Issue 11, pp. 4029-38, (2009) (PubMed).
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Epigenetic gene silencing by the SRY protein is mediated by a KRAB-O protein that recruits the KAP1 co-repressor machinery." in: The Journal of biological chemistry, Vol. 284, Issue 51, pp. 35670-80, (2009) (PubMed).
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- 抗原
- SRY (Sex Determining Region Y (SRY))
- 别名
- SRY (SRY 产品)
- 别名
- SRXX1 antibody, SRXY1 antibody, TDF antibody, TDY antibody, SRYGENE antibody, Sry1 antibody, Sry3BI antibody, Tdf antibody, Tdy antibody, SRY antibody, sex determining region Y antibody, sex determining region of Chr Y antibody, SRY antibody, Sry antibody
- 背景
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Description: This intronless gene encodes a transcription factor that is a member of the high mobility group (HMG)-box family of DNA-binding proteins. This protein is the testis-determining factor (TDF), which initiates male sex determination. Mutations in this gene give rise to XY females with gonadal dysgenesis (Swyer syndrome), translocation of part of the Y chromosome containing this gene to the X chromosome causes XX male syndrome.
Aliases: TDF, TDY, SRXX1, SRXY1
- 分子量
- 23.9 kDa
- 基因ID
- 6736
- HGNC
- 6736
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