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GZMB 抗体

GZMB 适用: 人 ELISA, FACS, cELISA 宿主: 小鼠 Monoclonal GM-4C1 unconjugated
产品编号 ABIN108719
发货至: 中国
  • 抗原 See all GZMB 抗体
    GZMB (Granzyme B (GZMB))
    适用
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    宿主
    • 83
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    小鼠
    克隆类型
    • 81
    • 48
    单克隆
    标记
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    This GZMB antibody is un-conjugated
    应用范围
    • 71
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    ELISA, Flow Cytometry (FACS), Cell-ELISA (cELISA)
    特异性
    GM4C1 recognises granzyme B transiently expressed on the cell surface of transfected BOSC cells as well as the native protein in peripheral blood mononuclear cells. The antibody does not cross-react with the human granzymes A, K or M (Fi
    纯化方法
    Protein G
    免疫原
    genetic immunisation with cDNA encoding human Granzyme B
    克隆位点
    GM-4C1
    亚型
    IgG1
    Top Product
    Discover our top product GZMB Primary Antibody
  • 应用备注
    Flow cytometry: 1.2 µg/10^6 cells
    ELISA: 1:200 - 1:400
    CELISA: 1:200 - 1:400
    For each application a titration should be performed to determine the optimal concentration.
    限制
    仅限研究用
  • 缓冲液
    PBS, pH 7.2
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C
    储存方法
    short term: 2 °C - 8 °C, long term: -20 °C
  • 抗原
    GZMB (Granzyme B (GZMB))
    别名
    Granzyme B (GZMB 产品)
    别名
    CCPI antibody, CGL-1 antibody, CGL1 antibody, CSP-B antibody, CSPB antibody, CTLA1 antibody, CTSGL1 antibody, HLP antibody, SECT antibody, granzyme B antibody, GZMB antibody
    背景
    Granzymes are exogenous serine proteases that are stored in the cytotoxic granules of activated T cells and NK cells. GM4C1 was generated by genetic immunisation and reacts with human granzyme B (GrB), a 27 kDa serine protease which cleaves target-cell proteins at specific aspartate residues.
    UniProt
    P10144
    途径
    Apoptosis, Caspase Cascade in Apoptosis
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