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- 抗原 See all CENPE 抗体
- CENPE (Centromere Protein E, 312kDa (CENPE))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This CENPE antibody is un-conjugated
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应用范围
- Immunoprecipitation (IP), Immunocytochemistry (ICC), Immunofluorescence (IF), Flow Cytometry (FACS)
- 纯化方法
- Affinity purified by ion exchange chromatography
- 免疫原
- Recombinant full length CENPE protein (human)
- 克隆位点
- 1H12
- 亚型
- IgG1 kappa
- Top Product
- Discover our top product CENPE Primary Antibody
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- 应用备注
- Optimal antibody dilution should be determined by titration, however as a guideline try IP: Use at μg/mg of lysate. Use at a concentration of 3 μg/mL per 300 μg of lysate WB: Use a concentration of 0.5 - 1 μg/mL. Predicted molecular weight: 312 kDa. Only suitable for WB if IP is performed first Flow CytFlow Cyt: Use 1 μg for 106 cells
- 说明
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Myeloma, fusion partners: SP2/0
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Purified antibody (from supernatant) containing PBS 0.1 % sodium azide,
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
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Midbody assembly and its regulation during cytokinesis." in: Molecular biology of the cell, Vol. 23, Issue 6, pp. 1024-34, (2012) (PubMed).
: "Small GTPase Rab5 participates in chromosome congression and regulates localization of the centromere-associated protein CENP-F to kinetochores." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 108, Issue 42, pp. 17337-42, (2011) (PubMed).
: "Aurora kinases and protein phosphatase 1 mediate chromosome congression through regulation of CENP-E." in: Cell, Vol. 142, Issue 3, pp. 444-55, (2010) (PubMed).
: "Telomere disruption results in non-random formation of de novo dicentric chromosomes involving acrocentric human chromosomes." in: PLoS genetics, Vol. 6, Issue 8, (2010) (PubMed).
: "Mediator of DNA damage checkpoint 1 (MDC1) regulates mitotic progression." in: The Journal of biological chemistry, Vol. 284, Issue 49, pp. 33939-48, (2009) (PubMed).
: "Glycogen synthase kinase 3beta interacts with and phosphorylates the spindle-associated protein astrin." in: The Journal of biological chemistry, Vol. 283, Issue 4, pp. 2454-64, (2008) (PubMed).
: "PIASgamma is required for faithful chromosome segregation in human cells." in: PLoS ONE, Vol. 1, pp. e53, (2007) (PubMed).
: "Farnesyl transferase inhibitors impair chromosomal maintenance in cell lines and human tumors by compromising CENP-E and CENP-F function." in: Molecular cancer therapeutics, Vol. 6, Issue 4, pp. 1317-28, (2007) (PubMed).
: "Tankyrase-1 polymerization of poly(ADP-ribose) is required for spindle structure and function." in: Nature cell biology, Vol. 7, Issue 11, pp. 1133-9, (2005) (PubMed).
: "CENP-E, a novel human centromere-associated protein required for progression from metaphase to anaphase." in: The EMBO journal, Vol. 10, Issue 5, pp. 1245-54, (1991) (PubMed).
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Midbody assembly and its regulation during cytokinesis." in: Molecular biology of the cell, Vol. 23, Issue 6, pp. 1024-34, (2012) (PubMed).
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- 抗原
- CENPE (Centromere Protein E, 312kDa (CENPE))
- 别名
- CENPE (CENPE 产品)
- 别名
- CENP-E antibody, KIF10 antibody, PPP1R61 antibody, 312kDa antibody, AU019344 antibody, BC049989 antibody, C530022J18 antibody, Kif10 antibody, CENPE antibody, kif10 antibody, cenp-E antibody, XCENP-E antibody, wu:fc06a10 antibody, zgc:152925 antibody, centromere protein E antibody, centromere protein E, 312kDa antibody, CENPE antibody, Cenpe antibody, cenpe antibody
- 背景
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Synonyms:
CENP E antibody,Centromere autoantigen E antibody,Centromere protein E 312kDa antibody,Centromereprotein E antibody,Centromeric protein E antibody,KIF10 antibody,Kinesin family member 10 antibody,Kinesinrelated protein antibody - 基因ID
- 1062, 296137
- OMIM
- 117143
- UniProt
- O08901
- 途径
- M Phase, Maintenance of Protein Location
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