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CENPE 抗体

CENPE 适用: 人 IP, ICC, IF, FACS 宿主: 小鼠 Monoclonal 1H12 unconjugated
产品编号 ABIN108562
发货至: 中国
  • 抗原 See all CENPE 抗体
    CENPE (Centromere Protein E, 312kDa (CENPE))
    适用
    • 37
    • 3
    • 2
    宿主
    • 29
    • 6
    • 3
    小鼠
    克隆类型
    • 32
    • 6
    单克隆
    标记
    • 21
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CENPE antibody is un-conjugated
    应用范围
    • 24
    • 18
    • 7
    • 6
    • 5
    • 5
    • 1
    • 1
    Immunoprecipitation (IP), Immunocytochemistry (ICC), Immunofluorescence (IF), Flow Cytometry (FACS)
    纯化方法
    Affinity purified by ion exchange chromatography
    免疫原
    Recombinant full length CENPE protein (human)
    克隆位点
    1H12
    亚型
    IgG1 kappa
    Top Product
    Discover our top product CENPE Primary Antibody
  • 应用备注
    Optimal antibody dilution should be determined by titration, however as a guideline try IP: Use at μg/mg of lysate. Use at a concentration of 3 μg/mL per 300 μg of lysate WB: Use a concentration of 0.5 - 1 μg/mL. Predicted molecular weight: 312 kDa. Only suitable for WB if IP is performed first Flow CytFlow Cyt: Use 1 μg for 106 cells
    说明

    Myeloma, fusion partners: SP2/0

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Purified antibody (from supernatant) containing PBS 0.1 % sodium azide,
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
  • Hu, Coughlin, Mitchison: "Midbody assembly and its regulation during cytokinesis." in: Molecular biology of the cell, Vol. 23, Issue 6, pp. 1024-34, (2012) (PubMed).

    Serio, Margaria, Jensen, Oldani, Bartek, Bussolino, Lanzetti: "Small GTPase Rab5 participates in chromosome congression and regulates localization of the centromere-associated protein CENP-F to kinetochores." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 108, Issue 42, pp. 17337-42, (2011) (PubMed).

    Kim, Holland, Lan, Cleveland: "Aurora kinases and protein phosphatase 1 mediate chromosome congression through regulation of CENP-E." in: Cell, Vol. 142, Issue 3, pp. 444-55, (2010) (PubMed).

    Stimpson, Song, Jauch, Holtgreve-Grez, Hayden, Bridger, Sullivan: "Telomere disruption results in non-random formation of de novo dicentric chromosomes involving acrocentric human chromosomes." in: PLoS genetics, Vol. 6, Issue 8, (2010) (PubMed).

    Townsend, Mason, Blackford, Miller, Chapman, Sedgwick, Barone, Turnell, Stewart: "Mediator of DNA damage checkpoint 1 (MDC1) regulates mitotic progression." in: The Journal of biological chemistry, Vol. 284, Issue 49, pp. 33939-48, (2009) (PubMed).

    Cheng, Hsiao, Lin, Yu, Hsu, Chang, Lee, Huang, Howng, Hong: "Glycogen synthase kinase 3beta interacts with and phosphorylates the spindle-associated protein astrin." in: The Journal of biological chemistry, Vol. 283, Issue 4, pp. 2454-64, (2008) (PubMed).

    Díaz-Martínez, Giménez-Abián, Azuma, Guacci, Giménez-Martín, Lanier, Clarke: "PIASgamma is required for faithful chromosome segregation in human cells." in: PLoS ONE, Vol. 1, pp. e53, (2007) (PubMed).

    Schafer-Hales, Iaconelli, Snyder, Prussia, Nettles, El-Naggar, Khuri, Giannakakou, Marcus: "Farnesyl transferase inhibitors impair chromosomal maintenance in cell lines and human tumors by compromising CENP-E and CENP-F function." in: Molecular cancer therapeutics, Vol. 6, Issue 4, pp. 1317-28, (2007) (PubMed).

    Chang, Coughlin, Mitchison: "Tankyrase-1 polymerization of poly(ADP-ribose) is required for spindle structure and function." in: Nature cell biology, Vol. 7, Issue 11, pp. 1133-9, (2005) (PubMed).

    Yen, Compton, Wise, Zinkowski, Brinkley, Earnshaw, Cleveland: "CENP-E, a novel human centromere-associated protein required for progression from metaphase to anaphase." in: The EMBO journal, Vol. 10, Issue 5, pp. 1245-54, (1991) (PubMed).

  • 抗原
    CENPE (Centromere Protein E, 312kDa (CENPE))
    别名
    CENPE (CENPE 产品)
    别名
    CENP-E antibody, KIF10 antibody, PPP1R61 antibody, 312kDa antibody, AU019344 antibody, BC049989 antibody, C530022J18 antibody, Kif10 antibody, CENPE antibody, kif10 antibody, cenp-E antibody, XCENP-E antibody, wu:fc06a10 antibody, zgc:152925 antibody, centromere protein E antibody, centromere protein E, 312kDa antibody, CENPE antibody, Cenpe antibody, cenpe antibody
    背景
    Synonyms:
    CENP E antibody,Centromere autoantigen E antibody,Centromere protein E 312kDa antibody,Centromereprotein E antibody,Centromeric protein E antibody,KIF10 antibody,Kinesin family member 10 antibody,Kinesinrelated protein antibody
    基因ID
    1062, 296137
    OMIM
    117143
    UniProt
    O08901
    途径
    M Phase, Maintenance of Protein Location
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