SDPR 抗体 (N-Term)
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- 抗原 See all SDPR 抗体
- SDPR (Serum Deprivation Response (SDPR))
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抗原表位
- N-Term
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This SDPR antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA
- 特异性
- It is predicted to not cross-react with other members of the cavin family.
- 纯化方法
- Affinity chromatography purified via peptide column
- 免疫原
- Rabbit polyclonal SDPR antibody was raised against an 18 amino acid peptide near the amino terminus of human SDPR.
- 亚型
- IgG
- Top Product
- Discover our top product SDPR Primary Antibody
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- 应用备注
- SDPR antibody can be used for detection of SDPR by Western blot at 1 - 2 μg/mL.
- 说明
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(NT) Serum deprivation-response protein
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- PBS containing 0.02 % Sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
- 储存条件
- 4 °C/-20 °C
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- 抗原
- SDPR (Serum Deprivation Response (SDPR))
- 别名
- SDPR (SDPR 产品)
- 别名
- CAVIN2 antibody, PS-p68 antibody, SDR antibody, cavin-2 antibody, sdr antibody, MGC84112 antibody, sdprb antibody, wu:fb39c08 antibody, wu:fk90b02 antibody, zgc:92231 antibody, caveolae associated protein 2 antibody, caveolae associated 2 antibody, caveolae associated protein 2 S homeolog antibody, serum deprivation response antibody, caveolae associated protein 2b antibody, CAVIN2 antibody, Cavin2 antibody, cavin2.S antibody, SDPR antibody, cavin2b antibody
- 背景
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The serum deprivation-response protein (SDPR) is a calcium-independent phospholipid-binding protein whose expression is increased in serum-starved cells. SDPR is a substrate for protein kinase C (PKC) phosphorylation and recruits the polymerase I and transcript release factor (PTRF) to caveolae. Removal of this protein causes caveolae loss and its over-expression results in caveolae deformation and membrane tubulation. Both SDPR and PTRF, as well as the other member of the cavin family PRKCDBP were down regulated in breast cancer cell lines and breast tumor tissue, suggesting that expression of the cavin family proteins could be a useful prognostic indicator of breast cancer progression.
Synonyms: Serum deprivation response, SDR, serum deprivation-response protein, CAVIN2, PS-p68, cavin-2, phosphatidylserine binding protein - 分子量
- 47 kDa
- 基因ID
- 8436
- NCBI登录号
- NP_004648
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