KREMEN1 抗体 (C-Term)
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- 抗原 See all KREMEN1 抗体
- KREMEN1 (Kringle Containing Transmembrane Protein 1 (KREMEN1))
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抗原表位
- C-Term
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This KREMEN1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA
- 特异性
- Three isoforms of KREMEN1 exists as a result of alternative splicing event.
- 纯化方法
- Affinity chromatography purified via peptide column
- 免疫原
- Rabbit polyclonal KREMEN1 antibody was raised against an 18 amino acid peptide near the carboxy terminus of human KREMEN1.
- 亚型
- IgG
- Top Product
- Discover our top product KREMEN1 Primary Antibody
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- 应用备注
- KREMEN1 antibody can be used for detection of KREMEN1 by Western blot at 0.5 - 1 μg/mL.
- 说明
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(CT) Kringle-containing protein marking the eye and the nose
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- PBS containing 0.02 % Sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
- 储存条件
- 4 °C/-20 °C
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- 抗原
- KREMEN1 (Kringle Containing Transmembrane Protein 1 (KREMEN1))
- 别名
- KREMEN1 (KREMEN1 产品)
- 别名
- KREMEN1 antibody, krm1 antibody, kremen antibody, kremem1 antibody, KREMEN antibody, KRM1 antibody, AV002070 antibody, Kremen antibody, Krm1 antibody, si:ct737139.1 antibody, si:dkeyp-7c9.1 antibody, kringle containing transmembrane protein 1 antibody, kringle containing transmembrane protein 1 S homeolog antibody, KREMEN1 antibody, kremen1 antibody, Kremen1 antibody, kremen1.S antibody
- 背景
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Kremen (Kringle containing protein marking the eye and the nose) proteins are type I transmembrane proteins that contain extracellular kringle, WSC and CUB domains and an intracellular region without any conserved motifs. Kremens bind a subset of the secreted Dickkopf proteins (Dkk 1, 2, and 4) with high affinity to modulate the canonical Wnt signaling pathway that is transduced by the ternary receptor complex composed of Wnt, Frizzled, and the LDL receptor related protein 5/6 (LRP5/6) coreceptor. KREMEN1 is a receptor for the Dickkopf protein which blocks Wnt/beta catenin signaling. It is necessary to ensure normal spatial and temporal patterns of Wnt activity during developmental processes.
Synonyms: Kringle-containing protein marking the eye and the nose, Kringle containing transmembrane protein 1, KRM1, Dickkopf receptor - 分子量
- 54 kDa
- 基因ID
- 83999
- NCBI登录号
- NP_114434
- 途径
- WNT signaling
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