IL-15 抗体
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- 抗原 See all IL-15 (IL15) 抗体
- IL-15 (IL15) (Interleukin 15 (IL15))
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 单克隆
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标记
- This IL-15 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA
- 特异性
- At least two isoforms of IL-15 are known to exist.
- 纯化方法
- Affinity chromatography purified via peptide column
- 免疫原
- Rabbit polyclonal IL-15 antibody was raised against a 13 amino acid peptide near the center of human IL-15.
- 亚型
- IgG
- Top Product
- Discover our top product IL15 Primary Antibody
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- 应用备注
- IL-15 antibody can be used for detection of IL-15 by Western blot at 1 - 2 μg/mL.
- 说明
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(IN) Interleukin-15
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- PBS containing 0.02 % Sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
- 储存条件
- 4 °C/-20 °C
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- 抗原
- IL-15 (IL15) (Interleukin 15 (IL15))
- 别名
- IL15 (IL15 产品)
- 别名
- IL15 antibody, AI503618 antibody, IL-15 antibody, interleukin 15 antibody, IL15 antibody, Il15 antibody
- 背景
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Interleukin 15 (IL-15) is a cytokine that regulates T and natural killer cell activation and proliferation. This cytokine and IL-2 share many biological activities as both have been found to bind common hematopoietin receptor subunits, and may compete for the same receptor, and thus negatively regulate each other's activity. The number of CD8+ memory cells is shown to be controlled by a balance between IL-15 and IL-2. This cytokine induces the activation of JAK kinases, as well as the phosphorylation and activation of transcription activators STAT3, STAT5, and STAT6. In mouse, studies suggest that IL-15 may increase the expression of apoptosis inhibitor Bcl-xL, possibly through the transcription activation activity of STAT6, and thus prevent apoptosis.
Synonyms: Interleukin-15, IL15 - 分子量
- 18 kDa
- 基因ID
- 3600
- NCBI登录号
- NP_000576
- 途径
- JAK/STAT Signaling, Glycosaminoglycan Metabolic Process
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