MECR 抗体 (C-Term)
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- 抗原 See all MECR 抗体
- MECR (Mitochondrial Trans-2-Enoyl-CoA Reductase (MECR))
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抗原表位
- C-Term
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This MECR antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA
- 特异性
- At least two isoforms of MECR are known to exist, this antibody will detect both isoforms.
- 纯化方法
- Affinity chromatography purified via peptide column
- 免疫原
- Rabbit polyclonal MECR antibody was raised against a 15 amino acid peptide near the carboxy terminus of human MECR.
- 亚型
- IgG
- Top Product
- Discover our top product MECR Primary Antibody
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- 应用备注
- MECR antibody can be used for detection of MECR by Western blot at 1 - 2 μg/mL.
- 说明
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(CT) Mitochondrial trans-2-enoyl-CoA reductase
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- PBS containing 0.02 % Sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- MECR antibody can be stored at 4 °C for three months. At -20 °C stable for up to one year.
- 有效期
- 12 months
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- 抗原
- MECR (Mitochondrial Trans-2-Enoyl-CoA Reductase (MECR))
- 别名
- MECR (MECR 产品)
- 别名
- CGI-63 antibody, FASN2B antibody, NRBF1 antibody, AI195831 antibody, Nrbf1 antibody, mitochondrial trans-2-enoyl-CoA reductase antibody, MECR antibody, Mecr antibody
- 背景
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The mitochondrial trans-2-enoyl-CoA reductase (MECR), was initially identified as nuclear receptor-binding factor 1 (NRBF1), which can interact with a multitude of nuclear hormone receptors in the presence of the respective ligands. MECR has been shown to be part of the mitochondrial fatty acid synthesis (FAS II) system and to catalyze the NAPDH-dependent reduction of 2-enoyl thioesters, generating saturated acyl-groups. Overexpression of this gene in transgenic mice can lead to cardiac abnormalities, suggesting that inappropriate expression of genes of FAS II can result in the development of hereditary cardiomyopathy.
Synonyms: Mitochondrial trans-2-enoyl-CoA reductase, nuclear receptor-binding factor 1, NRBF1, CGI-63, FASN2B - 分子量
- 41 kDa (calculated)
- 基因ID
- 51102
- NCBI登录号
- NP_057095
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