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TLK1 抗体 (Isoform 1)

TLK1 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN107632
发货至: 中国
  • 抗原 See all TLK1 抗体
    TLK1 (Tousled-Like Kinase 1 (TLK1))
    抗原表位
    • 15
    • 12
    • 8
    • 8
    • 7
    • 6
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 737-751, Isoform 1
    适用
    • 56
    • 48
    • 31
    • 5
    • 5
    • 5
    • 5
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    宿主
    • 75
    • 2
    克隆类型
    • 76
    • 1
    多克隆
    标记
    • 35
    • 5
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This TLK1 antibody is un-conjugated
    应用范围
    • 58
    • 31
    • 13
    • 13
    • 11
    • 8
    • 5
    • 5
    • 3
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA
    产品特性
    Concentration Definition: by UV absorbance at 280 nm
    免疫原
    This affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to amino acids 737-751 of human Tlk1 (Tousled-like kinase) protein.
    亚型
    IgG
    Top Product
    Discover our top product TLK1 Primary Antibody
  • 应用备注
    This affinity purified antibody has been tested for use in ELISA and by western blot.  Specific conditions for reactivity should be optimized by the end user. Expect a band approximately 86 kDa, 89 kDa or 64 kDa in size corresponding to isoforms of TLk-1 by western blotting in the appropriate cell lysate or extract.  This antibody reacts with both phosphorylated and non-phosphorylated forms of Tlk-1 at the S743 residue (isoform 1) of the protein.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.60 mg/mL
    缓冲液
    0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
  • 抗原
    TLK1 (Tousled-Like Kinase 1 (TLK1))
    别名
    Tlk1 (TLK1 产品)
    别名
    PKU-beta antibody, 4930545J15Rik antibody, fe11e12 antibody, si:dkey-251e16.4 antibody, tlk1 antibody, wu:fe11e12 antibody, TLK1 antibody, fb76h12 antibody, si:dkey-88m1.1 antibody, wu:fb76h12 antibody, DKFZp459L163 antibody, tousled like kinase 1 antibody, tousled-like kinase 1 antibody, tousled-like kinase 1b antibody, tousled like kinase 1 like antibody, serine/threonine-protein kinase TOUSLED antibody, tousled-like kinase 1a antibody, Serine/threonine-protein kinase tousled-like 1 antibody, TLK1 antibody, Tlk1 antibody, tlk1b antibody, TLK1L antibody, LOC542181 antibody, tlk1a antibody, tlk1 antibody, tlk-1 antibody
    背景
    Tlk-1 (also known as tousled-like kinase, serine/threonine-protein kinase tousled-like 1 and PKU-beta) is a target for Chk1 upon induction of DNA-damage. Tousled-like kinases, first described in Arabadopsis, are nuclear serine/threonine kinases that are potentially involved in the regulation of chromatin assembly. Tlk-1 is rapidly and transiently inhibited by phosphorylation following the generation of DNA double-stranded breaks during S-phase. This is cell cycle checkpoint and ATM-pathway dependent.  Tlk-1 heterodimerizes with Tlk-2.  Multiple isoforms of the protein have been detected.  Mature Tlk-1 is reported to have an apparent molecular weight of ~86kDa, ~89kDa and ~64kDa corresponding to isoforms 1, 2 and 3 respectively.
    Synonyms: PKU beta antibody, serine threonine protein kinase antibody, Serine/threonine protein kinase tousled like 1 antibody, TLK1 antibody, Tousled like kinase 1 antibody
    基因ID
    9874, 33636698
    UniProt
    Q9UKI8
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