电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

TLK1 抗体 (AA 730-755)

Rockland 600-401-469 TLK1 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
Rockland
产品编号 ABIN107632
Supplier Product No.: 600-401-469
发货至: 中国
  • 抗原 See all TLK1 抗体
    TLK1 (Tousled-Like Kinase 1 (TLK1))
    抗原表位
    • 15
    • 8
    • 8
    • 7
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 730-755
    适用
    • 44
    • 40
    • 30
    • 5
    • 5
    • 5
    • 4
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    宿主
    • 62
    • 2
    克隆类型
    • 63
    • 1
    多克隆
    标记
    • 33
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This TLK1 antibody is un-conjugated
    应用范围
    • 51
    • 26
    • 13
    • 13
    • 11
    • 8
    • 5
    • 5
    • 3
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA
    Supplier Product No.
    600-401-469
    Supplier
    Rockland
    原理
    Tlk1 Antibody
    交叉反应 (详细)
    This affinity purified antibody is directed against human Tlk-1 protein.
    产品特性
    Synonyms: rabbit anti-TLK1 antibody, TLK-1, TLK 1, PKU-beta antibody, serine threonine protein kinase antibody, Serine/threonine protein kinase tousled like 1 antibody, Tousled like kinase 1 antibody
    纯化方法
    The product was affinity purified from monospecific antiserum by immunoaffinity purification.
    过滤
    Sterile filtered
    免疫原

    Immunogen: This affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to a C-Terminal region near amino acids 730-755 of human Tlk1 (Tousled-like kinase) (isoform 1) protein.

    Immunogen Type: Conjugated Peptide

    亚型
    IgG
    Top Product
    Discover our top product TLK1 Primary Antibody
  • 应用备注

    Application Note: This affinity purified antibody has been tested for use in ELISA and by western blot.  Specific conditions for reactivity should be optimized by the end user. Expect a band approximately 86 kDa, 89 kDa or 64 kDa in size corresponding to isoforms of TLk-1 by western blotting in the appropriate cell lysate or extract.  This antibody reacts with both phosphorylated and non-phosphorylated forms of Tlk-1 at the S743 residue (isoform 1) of the protein.

    Western Blot Dilution: 1:200 - 1:2,000

    ELISA Dilution: 1:10,000 - 1:50,000

    Other: User Optimized

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.60 mg/mL
    缓冲液

    Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

    Stabilizer: None

    Preservative: 0.01 % (w/v) Sodium Azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
    有效期
    12 months
  • 抗原
    TLK1 (Tousled-Like Kinase 1 (TLK1))
    别名
    TLK1 (TLK1 产品)
    背景
    Background: Tlk-1 (also known as tousled-like kinase, serine/threonine-protein kinase tousled-like 1 and PKU-beta) is a target for Chk1 upon induction of DNA-damage. Tousled-like kinases, first described in Arabadopsis, are nuclear serine/threonine kinases that are potentially involved in the regulation of chromatin assembly. Tlk-1 is rapidly and transiently inhibited by phosphorylation following the generation of DNA double-stranded breaks during S-phase. This is cell cycle checkpoint and ATM-pathway dependent.  Tlk-1 heterodimerizes with Tlk-2.  Multiple isoforms of the protein have been detected.  Mature Tlk-1 is reported to have an apparent molecular weight of ~86 kDa, ~89 kDa and ~64 kDa corresponding to isoforms 1, 2 and 3 respectively.
    基因ID
    9874, 33636698
    UniProt
    Q9UKI8
You are here:
客服