(1 reference)-
- 抗原 See all Pyruvate Kinase (PK) 抗体
- Pyruvate Kinase (PK)
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适用
- 兔
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宿主
- 山羊
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克隆类型
- 多克隆
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标记
- This Pyruvate Kinase antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunoprecipitation (IP), Conjugation (Con), Dot Blot (DB)
- 产品特性
- Concentration Definition: by Refractometry
- 纯化方法
- This product was prepared from monospecific antiserum by a delipidation and defibrination. Assay by immunoelectrophoresis resulted in a single precipitin arc against purified and partially purified Pyruvate Kinase [Rabbit Muscle].
- 免疫原
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Pyruvate Kinase [Rabbit Muscle]
Immunogentype:Native - Top Product
- Discover our top product PK Primary Antibody
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anti-Pyruvate Kinase (PK) (Center) antibody
PK 适用: 人, 大鼠 WB, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-Pyruvate Kinase (PK) (AA 476-505), (C-Term) antibodyPK 适用: 人, 小鼠, 大鼠, 猴 WB, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Pyruvate Kinase (PK) antibodyPK 适用: 人, 小鼠, 大鼠, 猴 WB, IHC, IF/ICC 宿主: 兔 Polyclonal unconjugated
anti-Pyruvate Kinase (PK) antibody (Biotin)PK 适用: 兔 WB, ELISA 宿主: 山羊 Polyclonal Biotin
anti-Pyruvate Kinase (PK) (AA 121-151), (N-Term) antibodyPK 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Pyruvate Kinase (PK) (AA 476-505), (C-Term) antibodyPK 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Anti-PYRUVATE KINASE Antibody is suitable for immunoblotting (western or dot blot), ELISA, immunoprecipitation, conjugation and most immunological methods requiring high titer and specificity. Specific conditions should be optimized by user.
- 说明
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This product is for research use only and is not intended for therapeutic or diagnostic applications. Please contact a technical service representative for more information.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Restore with deionized water (or equivalent)
- 浓度
- 40 mg/mL
- 缓冲液
- 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
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: "Modulation of M2-type pyruvate kinase activity by the cytoplasmic PML tumor suppressor protein." in: Genes to cells : devoted to molecular & cellular mechanisms, Vol. 13, Issue 3, pp. 245-54, (2008) (PubMed).
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: "Modulation of M2-type pyruvate kinase activity by the cytoplasmic PML tumor suppressor protein." in: Genes to cells : devoted to molecular & cellular mechanisms, Vol. 13, Issue 3, pp. 245-54, (2008) (PubMed).
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- 抗原
- Pyruvate Kinase (PK)
- 别名
- Pyruvate Kinase (PK 产品)
- 别名
- CG7070 antibody, Dmel\\CG7070 antibody, PYK antibody, Pyk antibody, PYK3b antibody, PYK3c antibody, Pyruvate kinase antibody, PK antibody, pyruvate kinase antibody, pyruvate kinase (PK) antibody, Pyruvate kinase (PK) antibody, pyruvate kinase PKM antibody, testis expressed 45 antibody, PyK antibody, pykA antibody, PYK3a|PYK3b|PYK3c antibody, pyk antibody, pyk1 antibody, pk antibody, LOC100534543 antibody, TEX45 antibody
- 背景
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Pyruvate kinase (EC: 2.7.1.40) is an enzyme involved in glycolysis. It catalyzes the transfer of a phosphate group from phosphoenolpyruvate (PEP) to ADP, yielding one molecule of pyruvate and one molecule of ATP. This process also requires a magnesium ion. The enzyme is a 'transferase' under the international classification of enzymes. This step is the final one in the glycolytic pathway, which produces pyruvate molecules, the final product of aerobic glycolysis. However, in anaerobic glycolysis, lactate dehydrogenase will utilize the NADH produced by glyceraldehyde phosphate dehydrogenase to reduce pyruvate to lactate. In humans, there are two pyruvate kinase isozymes: type M (muscle, SwissProt P14618) and type L,R (liver and erythrocyte, SwissProt P30613). The isozymes differ in primary structure and regulation. This reaction has a large positive free energy change, one of three in glycolysis. All three such steps regulate the overall activity of the pathway, and are, in general, irreversible under wild-type conditions. Anti-Pyruvate kinase antibody is idea for investigators involved in cytokines and growth factor research.
Synonyms: Pyruvate kinase isozymes M1/M2 antibody, Pyruvate kinase muscle isozyme antibody, Pyruvate kinase 2/3 antibody, Cytosolic thyroid hormone-binding protein antibody - 基因ID
- 100008676
- NCBI登录号
- NP_001182574
- UniProt
- P11974
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