ING4 抗体 (AA 150-175)
(2 references)
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- 抗原 See all ING4 抗体
- ING4 (Inhibitor of Growth Family, Member 4 (ING4))
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抗原表位
- AA 150-175
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适用
- 人
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宿主
- 山羊
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克隆类型
- 多克隆
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标记
- This ING4 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA
- Supplier Product No.
- 600-101-284
- Supplier
- Rockland
- 原理
- p29ING4 Antibody
- 交叉反应 （详细）
- Reactivity occurs against human p29 ING4 protein.
- 产品特性
- Synonyms: goat anti-p29 ING4 antibody, p29ING4, ING 4, ING-4, Inhibitor of growth family member 4 antibody, Inhibitor of growth family member 4 long isoform antibody, Inhibitor of growth protein 4 antibody, MGC12557 antibody
- 纯化方法
- This is an affinity purified antibody produced by immunoaffinity chromatography using the immunizing peptide after immobilization to a solid phase.
- 过滤
- Sterile filtered
- 免疫原
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Immunogen: This affinity purified antibody was prepared from whole goat serum produced by repeated immunizations with a synthetic peptide corresponding to an internal region near aa 150-175 of Human p29 ING4 protein (Inhibitor of growth family, member 4). This sequence only shows homology to isoform 1 for ING4.
Immunogen Type: Conjugated Peptide
- 亚型
- IgG
- Top Product
- Discover our top product ING4 Primary Antibody
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anti-Inhibitor of Growth Family, Member 4 (ING4) (AA 1-249) antibody
ING4 适用: 人 WB, IP, IF 宿主: 兔 Polyclonal unconjugated
anti-Inhibitor of Growth Family, Member 4 (ING4) (AA 1-249) antibodyING4 适用: 人 WB, IHC (p) 宿主: 小鼠 Polyclonal unconjugated
anti-Inhibitor of Growth Family, Member 4 (ING4) (AA 1-249) antibodyING4 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 8F7 unconjugated
anti-Inhibitor of Growth Family, Member 4 (ING4) (AA 110-159) antibodyING4 适用: 人, 小鼠, 大鼠, 犬, Cow, 兔, 猴, Pig WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Inhibitor of Growth Family, Member 4 (ING4) (AA 1-190) antibodyING4 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Inhibitor of Growth Family, Member 4 (ING4) (AA 162-195), (C-Term) antibodyING4 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB47839 unconjugated
anti-Inhibitor of Growth Family, Member 4 (ING4) (AA 75-249) antibodyING4 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Inhibitor of Growth Family, Member 4 (ING4) (Internal Region) antibodyING4 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Inhibitor of Growth Family, Member 4 (ING4) (Internal Region) antibodyING4 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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Application Note: This affinity-purified antibody has been tested for use in ELISA against the immunizing peptide. Specific conditions for western blotting reactivity should be optimized by the end user. Expect a band at approximately 29 kDa in size corresponding to ING4 isoform 1 by western blotting in the appropriate cell lysate or extract.
Western Blot Dilution: 1:500 - 1:3,000
ELISA Dilution: 1:3,000 - 1:12,000
Other: User Optimized
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1.28 mg/mL
- 缓冲液
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Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Stabilizer: None
Preservative: 0.01 % (w/v) Sodium Azide - 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
- 有效期
- 12 months
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: "The new tumor-suppressor gene inhibitor of growth family member 4 (ING4) regulates the production of proangiogenic molecules by myeloma cells and suppresses hypoxia-inducible factor-1 alpha ..." in: Blood, Vol. 110, Issue 13, pp. 4464-75, (2007) (PubMed).
: "Novel splice variants of ING4 and their possible roles in the regulation of cell growth and motility." in: The Journal of biological chemistry, Vol. 281, Issue 45, pp. 34677-86, (2006) (PubMed).
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: "The new tumor-suppressor gene inhibitor of growth family member 4 (ING4) regulates the production of proangiogenic molecules by myeloma cells and suppresses hypoxia-inducible factor-1 alpha ..." in: Blood, Vol. 110, Issue 13, pp. 4464-75, (2007) (PubMed).
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- 抗原
- ING4 (Inhibitor of Growth Family, Member 4 (ING4))
- 别名
- ING4 (ING4 产品)
- 背景
- Background: p29 ING4 is a tumor suppressor protein similar to ING1 that may inhibit tumor progression by modulating the transcriptional output of signaling pathways which regulate cell proliferation. p29 ING4 has been shown to suppress brain tumor angio-genesis through transcriptional repression of RelA/ NFKB3 target genes when complexed with RelA. p29 ING4 may also specifically suppress loss of contact inhibition elicited by activated oncogenes such as MYC. p29 ING4 shows a nuclear localization and interacts with EP300, TP53, RelA, inhibits cell growth, and induces apoptosis. This protein contains a PHD-finger, which is a common motif in proteins involved in chromatin remodeling. Multiple alternatively spliced transcript variants have been observed. The accession number listed below is for variant (1) that encodes the longest isoform.
- 基因ID
- 51147
- UniProt
- Q9UNL4
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