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SPRY2 抗体 (Internal Region)

SPRY2 适用: 人 WB, ELISA, IHC, IF, FM, MA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN1043909
发货至: 中国
  • 抗原 See all SPRY2 抗体
    SPRY2 (Sprouty Homolog 2 (SPRY2))
    抗原表位
    • 7
    • 6
    • 5
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region
    适用
    • 35
    • 21
    • 11
    • 8
    • 5
    • 4
    • 4
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    宿主
    • 35
    • 3
    • 1
    • 1
    克隆类型
    • 37
    • 3
    多克隆
    标记
    • 31
    • 3
    • 2
    • 2
    • 1
    • 1
    This SPRY2 antibody is un-conjugated
    应用范围
    • 32
    • 19
    • 13
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Fluorescence Microscopy (FM), Multiplex Assay (MA)
    原理
    Sprouty-2 Antibody
    交叉反应 (详细)
    Sprouty-2 antibody reacts with human Sprouty 2 protein.
    产品特性
    Synonyms: Rabbit anti-Sprouty2 antibody, Rabbit anti-Sprouty-2 antibody, Sprouty 2, SPRY2, SPRY 2, Spry-2, Protein sprouty homolog 2
    纯化方法
    Anti-Sprouty-2 was affinity purified from monospecific antiserum by immunoaffinity chromatography.
    过滤
    Sterile filtered
    免疫原

    Immunogen: Anti-Sprouty-2 affinity purified antibody was purified from monospecific rabbit antiserum prepared via repeated immunizations with peptide corresponding to an internal region of human sprouty-2.

    Immunogen Type: Conjugated Peptide

    亚型
    IgG
    Top Product
    Discover our top product SPRY2 Primary Antibody
  • 应用备注

    Immunohistochemistry Dilution: 10 μg/mL

    Application Note: Anti-Sprouty-2 antibody has been tested by ELISA, Immunofluorescence, Immunohistochemistry, and is suitable for western blotting. Specific conditions for reactivity should be optimized by the end user.

    Western Blot Dilution: 1:500-1:5,000

    ELISA Dilution: User Optimized

    IF Microscopy Dilution: User Optimized

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1.04 mg/mL
    缓冲液

    Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

    Stabilizer: None

    Preservative: 0.01 % (w/v) Sodium Azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
    有效期
    12 months
  • Zhang, Chaturvedi, Jaggar, Magnuson, Lee, Patel: "Regulation of vascular smooth muscle cell proliferation and migration by human sprouty 2." in: Arteriosclerosis, thrombosis, and vascular biology, Vol. 25, Issue 3, pp. 533-8, (2005) (PubMed).

    August: "Cerebrovascular and carotid artery disease." in: Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics, Vol. 92, Issue 3, pp. 253-6, (2001) (PubMed).

  • 抗原
    SPRY2 (Sprouty Homolog 2 (SPRY2))
    别名
    SPRY2 (SPRY2 产品)
    背景
    Background: Sprouty was originally identified as an inhibitor of Drosophila epidermal growth factor (EGF) and fibroblast growth factor (FGF) receptor signaling during tracheal development. Four isoforms of mammalian sprouty are known (Spry1-Spry4). The role of the mammalian analogs has not been clearly elucidated although it is believed that human Sprouty-2 (hSpry2) may be an inhibitor of cellular migration and proliferation. Spry2 and Spry4 show considerable sequence homology between human and mouse at the C-terminus of the protein. Significant sequence divergence occurs at the N-terminus. Spry2 appears to be abundant in brain, lung and heart tissue, with lesser amounts found in kidney and skeletal muscle.
    基因ID
    10253
    UniProt
    O43597
    途径
    EGFR Signaling Pathway, Sensory Perception of Sound, EGFR Downregulation
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