IL17F 抗体 (Biotin)
(1 reference)-
- 抗原 See all IL17F 抗体
- IL17F (Interleukin 17F (IL17F))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This IL17F antibody is conjugated to Biotin
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC)
- 特异性
- This product was purified from concentrated tissue culture supernate by Protein G chromatography followed by extensive dialysis against the buffer stated above. This antibody is specific for human IL-17F protein. A BLAST analysis was used to suggest cross-reactivity with IL-17F from human sources based on 100% homology with the immunizing sequence. Cross-reactivity with IL-17F from other sources has not been determined.
- 产品特性
- Anti-L-17F recognizes IL-17F (also known as Cytokine ML-1 or Interleukin-24). IL-17F is produced and secreted by CD8+ T cells, NK cells, NKT cells and LTi cells. The main functions of IL-17F are neutrophil recruitment and immunity to extracellular pathogen. More importantly, IL-17F drives inflammation and auto-immunity. IL-17A and IL-17F are by far the best characterized cytokines of the IL-17 cytokine family. IL-17F dimerizes in a parallel fashion similar to nerve growth factor and other neutrophins. Its dimerization is critical to fulfill its activity. When secreted by activated T cells, IL-17F can stimulate the production of other cytokines such as IL-6, IL-8 granulocyte colony-stimulating factor and, can stimulate cartilage matrix turnover. Defects in IL17F are the cause of familial candidiasis type 6 (CANDF6). CANDF6 is a rare disorder with altered immune responses and impaired clearance of fungal infections, selective against Candida. Anti-IL-17E cytokine antibody is ideal for investigators involved in Immunology, Signal Transduction research, Cancer and Inflammatory pathologies.
- 纯化方法
- purified
- 免疫原
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Anti-IL-17F (MOUSE) Monoclonal Antibody was produced in mouse by repeated immunizations with mature full length recombinant human IL-17F produced in E.coli followed by hybridoma development.
Immunogen Type: RecombinantProtein - 克隆位点
- 4H1629-1
- 亚型
- IgG1
- Top Product
- Discover our top product IL17F Primary Antibody
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anti-Interleukin 17F (IL17F) (AA 1-163) antibody
IL17F 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 17F (IL17F) (AA 1-163) antibodyIL17F 适用: 人 WB, IHC (p) 宿主: 小鼠 Polyclonal unconjugated
anti-Interleukin 17F (IL17F) antibodyIL17F 适用: 人 WB, IHC 宿主: 小鼠 Monoclonal 4H1629-1 unconjugated
anti-Interleukin 17F (IL17F) (AA 81-130) antibodyIL17F 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 17F (IL17F) (AA 31-163) antibodyIL17F 适用: 人 WB, IHC, ICC, IP 宿主: 小鼠 Monoclonal C8 unconjugated
anti-Interleukin 17F (IL17F) (AA 31-140) antibodyIL17F 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1E5 unconjugated
anti-Interleukin 17F (IL17F) (Internal Region) antibodyIL17F 适用: 人 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 17F (IL17F) antibody (Biotin)IL17F 适用: 人 WB, ELISA, Neut 宿主: 兔 Polyclonal Biotin
anti-Interleukin 17F (IL17F) antibody (HRP)IL17F 适用: 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal HRP
anti-Interleukin 17F (IL17F) (AA 16-45) antibodyIL17F 适用: 人 WB, ELISA, FACS 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- This purified antibody has been tested for use in IHC and Western Blot. Specific conditions for reactivity should be optimized by the end user.
- 说明
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Gene Name: IL17F
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Reconstitution Buffer: Restore with deionized water (or equivalent), Reconstitution Volume: 100 µL
- 浓度
- 1.0 mg/mL
- 缓冲液
- 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2, 10 mg/mL Bovine Serum Albumin (BSA) - Immunoglobulin and Protease free
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store vial at 4 °C prior to restoration. For extended storage aliquot contents and freeze at -20 °C or below. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4 °C as an undiluted liquid. Dilute only prior to immediate use. Expiration date is one (1) year from date of opening.
- 有效期
- 12 months
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: "Th17 cells and IL-17 receptor signaling are essential for mucosal host defense against oral candidiasis." in: The Journal of experimental medicine, Vol. 206, Issue 2, pp. 299-311, (2009) (PubMed).
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: "Th17 cells and IL-17 receptor signaling are essential for mucosal host defense against oral candidiasis." in: The Journal of experimental medicine, Vol. 206, Issue 2, pp. 299-311, (2009) (PubMed).
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- 抗原
- IL17F (Interleukin 17F (IL17F))
- 别名
- IL-17F (IL17F 产品)
- 别名
- CANDF6 antibody, IL-17F antibody, ML-1 antibody, ML1 antibody, C87042 antibody, IL17F antibody, interleukin 17F antibody, IL17F antibody, Il17f antibody
- 背景
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Anti-L-17F recognizes IL-17F (also known as Cytokine ML-1 or Interleukin-24). IL-17F is produced and secreted by CD8+ T cells, NK cells, NKT cells and LTi cells. The main functions of IL-17F are neutrophil recruitment and immunity to extracellular pathogen. More importantly, IL-17F drives inflammation and auto-immunity. IL-17A and IL-17F are by far the best characterized cytokines of the IL-17 cytokine family. IL-17F dimerizes in a parallel fashion similar to nerve growth factor and other neutrophins. Its dimerization is critical to fulfill its activity. When secreted by activated T cells, IL-17F can stimulate the production of other cytokines such as IL-6, IL-8 granulocyte colony-stimulating factor and, can stimulate cartilage matrix turnover. Defects in IL17F are the cause of familial candidiasis type 6 (CANDF6). CANDF6 is a rare disorder with altered immune responses and impaired clearance of fungal infections, selective against Candida. Anti-IL-17E cytokine antibody is ideal for investigators involved in Immunology, Signal Transduction research, Cancer and Inflammatory pathologies.
Synonyms: Interleukin-17F, Cytokine ML-1, Interleukin-24 - 基因ID
- 112744
- NCBI登录号
- NP_443104
- UniProt
- Q96PD4
- 途径
- Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Endopeptidase Activity
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