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Interleukin 17a 抗体

Rockland 209-301-b32 IL17A 适用: 人 ELISA, WB, FACS 宿主: 小鼠 Monoclonal 4H1524-1 unconjugated
Rockland
产品编号 ABIN1043781
Supplier Product No.: 209-301-b32
发货至: 中国
  • 抗原 See all Interleukin 17a (IL17A) 抗体
    Interleukin 17a (IL17A) (Interleukin 17A (IL17A))
    适用
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    宿主
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    小鼠
    克隆类型
    • 66
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    单克隆
    标记
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    This Interleukin 17a antibody is un-conjugated
    应用范围
    • 68
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    ELISA, Western Blotting (WB), Flow Cytometry (FACS)
    Supplier Product No.
    209-301-b32
    Supplier
    Rockland
    原理
    IL-17A Antibody
    交叉反应 (详细)
    This antibody is specific for human IL-17A protein.
    产品特性
    Synonyms: mouse anti-Interleukin-17A antibody, mouse anti-IL-17A antibody, IL-17A, Interleukin-17A, Cytotoxic T-Lymphocyte-associated Antigen 8, CTLA8, Interleukin-17, IL17, IL-17, Interleukin17
    纯化方法
    Anti-Human IL-17A (MOUSE) Monoclonal Antibody was purified from concentrated tissue culture supernate by Protein G chromatography followed by extensive dialysis against the buffer stated above.
    过滤
    Sterile filtered
    免疫原

    Immunogen: Anti-IL-17A (MOUSE) Monoclonal Antibody was produced in mouse by repeated immunizations with mature full length recombinant human IL-17A produced in E.coli followed by hybridoma development.

    Immunogen Type: Recombinant Protein

    克隆位点
    4H1524-1
    亚型
    IgG2b
    Top Product
    Discover our top product IL17A Primary Antibody
  • 应用备注

    Flow Cytometry Dilution: User Optimized

    Application Note: Anti-Human IL-17A antibody has been tested for use in Western Blot and suitable in FLOW. Specific conditions for reactivity should be optimized by the end user.

    Western Blot Dilution: 1 μg/mL

    ELISA Dilution: 1:10,000-1:50,000

    Other: User Optimized

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1.0 mg/mL
    缓冲液

    Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

    Stabilizer: None

    Preservative: 0.01 % (w/v) Sodium Azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
    有效期
    12 months
  • Paust, Turner, Steinmetz, Peters, Heymann, Hölscher, Wolf, Kurts, Mittrücker, Stahl, Panzer: "The IL-23/Th17 axis contributes to renal injury in experimental glomerulonephritis." in: Journal of the American Society of Nephrology : JASN, Vol. 20, Issue 5, pp. 969-79, (2009) (PubMed).

  • 抗原
    Interleukin 17a (IL17A) (Interleukin 17A (IL17A))
    别名
    IL17A (IL17A 产品)
    背景
    Background: IL17-A (also known as Interleukin-17) is a proinflammatory cytokine produced by activated T cells. This cytokine regulates the activities of NF-kappaB and mitogen-activated protein kinases. This cytokine can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO). High levels of this cytokine are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis. IL17-A is the founding member of a group of cytokines called the IL17 family. IL17-A was originally identified as a transcript from a rodent T-cell hybridoma. To elicit its functions, IL17 binds to a type I cell surface receptor called IL17R of which there are at least three variants IL17RA, IL17RB, and IL17RC. Anti-IL-17A antibody is ideal for investigators involved in Immunology research.
    基因ID
    3605
    UniProt
    Q16552
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