IL17F 抗体
(1 reference)
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- 抗原 See all IL17F 抗体
- IL17F (Interleukin 17F (IL17F))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This IL17F antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- Supplier Product No.
- 209-301-b31
- Supplier
- Rockland
- 原理
- IL-17F Antibody
- 交叉反应 （详细）
- This antibody is specific for human IL-17F protein.
- 产品特性
- Synonyms: mouse anti-IL-17F antibody, mouse anti-Interleukin-17F antibody, Cytokine ML-1, Interleukin-24
- 纯化方法
- Anti-Human IL-17F (MOUSE) Monoclonal Antibody was purified from concentrated tissue culture supernate by Protein G chromatography followed by extensive dialysis against the buffer stated above.
- 过滤
- Sterile filtered
- 免疫原
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Immunogen: Anti-IL-17F (MOUSE) Monoclonal Antibody was produced in mouse by repeated immunizations with mature full length recombinant human IL-17F produced in E.coli followed by hybridoma development.
Immunogen Type: Recombinant Protein
- 克隆位点
- 4H1629-1
- 亚型
- IgG1
- Top Product
- Discover our top product IL17F Primary Antibody
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anti-Interleukin 17F (IL17F) (AA 1-163) antibody
IL17F 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 17F (IL17F) (AA 1-163) antibodyIL17F 适用: 人 WB, IHC (p) 宿主: 小鼠 Polyclonal unconjugated
anti-Interleukin 17F (IL17F) (AA 81-130) antibodyIL17F 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 17F (IL17F) (AA 31-163) antibodyIL17F 适用: 人 WB, IHC, ICC, IP 宿主: 小鼠 Monoclonal C8 unconjugated
anti-Interleukin 17F (IL17F) (AA 31-140) antibodyIL17F 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1E5 unconjugated
anti-Interleukin 17F (IL17F) (Internal Region) antibodyIL17F 适用: 人 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 17F (IL17F) antibody (Biotin)IL17F 适用: 人 WB, ELISA, Neut 宿主: 兔 Polyclonal Biotin
anti-Interleukin 17F (IL17F) antibody (Biotin)IL17F 适用: 人 WB, ELISA, IHC 宿主: 小鼠 Monoclonal 4H1629-1 Biotin
anti-Interleukin 17F (IL17F) (AA 16-45) antibodyIL17F 适用: 人 WB, ELISA, FACS 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 17F (IL17F) (AA 31-163) antibodyIL17F 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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Immunohistochemistry Dilution: 5 μg/mL
Application Note: Anti-Human IL-17F antibody has been tested for use in IHC and Western Blot. Specific conditions for reactivity should be optimized by the end user.
Western Blot Dilution: 0.5 μg/mL
ELISA Dilution: 1:10,000-1:50,000
Other: User Optimized
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1.0mg/mL
- 缓冲液
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Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Stabilizer: None
Preservative: 0.01 % (w/v) Sodium Azide - 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
- 有效期
- 12 months
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: "Th17 cells and IL-17 receptor signaling are essential for mucosal host defense against oral candidiasis." in: The Journal of experimental medicine, Vol. 206, Issue 2, pp. 299-311, (2009) (PubMed).
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: "Th17 cells and IL-17 receptor signaling are essential for mucosal host defense against oral candidiasis." in: The Journal of experimental medicine, Vol. 206, Issue 2, pp. 299-311, (2009) (PubMed).
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- 抗原
- IL17F (Interleukin 17F (IL17F))
- 别名
- IL17F (IL17F 产品)
- 背景
- Background: Anti-L-17F recognizes IL-17F (also known as Cytokine ML-1 or Interleukin-24). IL-17F is produced and secreted by CD8+ T cells, NK cells, NKT cells and LTi cells. The main functions of IL-17F are neutrophil recruitment and immunity to extracellular pathogen. More importantly, IL-17F drives inflammation and auto-immunity. IL-17A and IL-17F are by far the best characterized cytokines of the IL-17 cytokine family. IL-17F dimerizes in a parallel fashion similar to nerve growth factor and other neutrophins. Its dimerization is critical to fulfill its activity. When secreted by activated T cells, IL-17F can stimulate the production of other cytokines such as IL-6, IL-8 granulocyte colony-stimulating factor and, can stimulate cartilage matrix turnover. Defects in IL17F are the cause of familial candidiasis type 6 (CANDF6). CANDF6 is a rare disorder with altered immune responses and impaired clearance of fungal infections, selective against Candida. Anti-IL-17E cytokine antibody is ideal for investigators involved in Immunology, Signal Transduction research, Cancer and Inflammatory pathologies.
- 基因ID
- 112744
- NCBI登录号
- NP_443104
- UniProt
- Q96PD4
- 途径
- Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Endopeptidase Activity
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