(1 reference)-
- 抗原 See all BIN3 抗体
- BIN3 (Bridging Integrator 3 (BIN3))
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适用
- 人, 小鼠
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This BIN3 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA
- 特异性
- Anti-BIN3 was purified from clarified mouse ascetic fluid by Protein A chromatography followed by extensive dialysis against the buffer stated above. BIN3 antibody is specific for human BIN3 protein. A BLAST analysis was used to suggest cross-reactivity with BIN3 from human and mouse sources based on 100% homology with the immunizing sequence. Cross-reactivity with BIN3 from other sources has not been determined.
- 产品特性
- BIN-3 encodes an evolutionarily conserved and ubiquitously expressed member of the BAR superfamily of curved membrane and GTPase-binding proteins implicated in signal transduction and vesicular trafficking. In humans, Bin3 maps to chromosome 8p21.3, a region widely implicated in cancer suppression that is often deleted in non-Hodgkin’s lymphomas and various epithelial tumors. Study in mouse suggests that homozygous inactivation of Bin3 causes cataracts and an increased susceptibility to lymphomas during aging.
- 过滤
- Sterile filtered
- 免疫原
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Anti-BIN3 (MOUSE) Monoclonal Antibody was produced in mouse by repeated immunizations with a GST tagged full legnth human BIN3 protein followed by hybridoma development.
Immunogen Type: RecombinantProtein - 克隆位点
- 3A4
- 亚型
- IgG1
- Top Product
- Discover our top product BIN3 Primary Antibody
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anti-Bridging Integrator 3 (BIN3) antibody
BIN3 适用: 人, 犬, 猴 WB, FACS, IF, IHC, IHC (p) 宿主: 小鼠 Monoclonal 8E9 unconjugated
anti-Bridging Integrator 3 (BIN3) antibodyBIN3 适用: 人, 大鼠, 犬, 猴 WB, FACS, IF, IHC, IHC (p) 宿主: 小鼠 Monoclonal 5E3 unconjugated
anti-Bridging Integrator 3 (BIN3) (AA 154-253) antibodyBIN3 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4E12 unconjugated
anti-Bridging Integrator 3 (BIN3) (AA 8-240) antibodyBIN3 适用: 人 ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Bridging Integrator 3 (BIN3) (AA 1-199) antibodyBIN3 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Bridging Integrator 3 (BIN3) (AA 1-199) antibodyBIN3 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3G3 unconjugated
anti-Bridging Integrator 3 (BIN3) (AA 1-200) antibodyBIN3 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1H8 unconjugated
anti-Bridging Integrator 3 (BIN3) (AA 1-253) antibodyBIN3 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Bridging Integrator 3 (BIN3) (AA 1-30), (N-Term) antibodyBIN3 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB21391 unconjugated
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- 应用备注
- Anti-BIN3 antibody has been tested for use in ELISA, Western Blot, and IP. Specific conditions for reactivity should be optimized by the end user.
- 说明
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Gene Name: BIN3
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1.0 mg/mL
- 缓冲液
- 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store vial at 4 °C prior to restoration. For extended storage aliquot contents and freeze at -20 °C or below. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4 °C as an undiluted liquid. Dilute only prior to immediate use. Expiration date is one (1) year from date of opening.
- 有效期
- 12 months
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: "Human BIN3 complements the F-actin localization defects caused by loss of Hob3p, the fission yeast homolog of Rvs161p." in: The Journal of biological chemistry, Vol. 276, Issue 24, pp. 21670-7, (2001) (PubMed).
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: "Human BIN3 complements the F-actin localization defects caused by loss of Hob3p, the fission yeast homolog of Rvs161p." in: The Journal of biological chemistry, Vol. 276, Issue 24, pp. 21670-7, (2001) (PubMed).
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- 抗原
- BIN3 (Bridging Integrator 3 (BIN3))
- 别名
- BIN3 (BIN3 产品)
- 别名
- 1700015F07Rik antibody, bridging integrator 3 antibody, BIN3 antibody, Bin3 antibody
- 背景
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BIN-3 encodes an evolutionarily conserved and ubiquitously expressed member of the BAR superfamily of curved membrane and GTPase-binding proteins implicated in signal transduction and vesicular trafficking. In humans, Bin3 maps to chromosome 8p21.3, a region widely implicated in cancer suppression that is often deleted in non–Hodgkin’s lymphomas and various epithelial tumors. Study in mouse suggests that homozygous inactivation of Bin3 causes cataracts and an increased susceptibility to lymphomas during aging.
Synonyms: Bridging integrator 3, BIN-3, BIN 3, BIN3 antibody, anti-BIN3 antibody - 基因ID
- 55909
- NCBI登录号
- NP_061158
- UniProt
- Q9NQY0
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