PPP2CA 抗体 (meLys309)
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- 抗原 See all PPP2CA 抗体
- PPP2CA (Protein Phosphatase 2, Catalytic Subunit, alpha Isozyme (PPP2CA))
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抗原表位
- meLys309
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适用
- 人, 小鼠, 大鼠
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This PPP2CA antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunoprecipitation (IP)
- 序列
- KLH-C-ßA-RRTPDYFL-OMe
- 特异性
- Recognises specifically the C-terminally methylated form of PP2A C subunit
- 交叉反应
- Saccharomyces cerevisiae
- 交叉反应 (详细)
- Mouse, Rat, Human. Predicted to work with: Saccharomyces cerevisiae
- 纯化方法
- Protein G
- 免疫原
- A KLH-coupled peptide with the sequence: KLH-C-ßA-RRTPDYFL-OMe. The c-terminal sequence (as well as the carboxy-methylation) is absolutely conserved from human, mouse to yeast
- 克隆位点
- 2A10
- 亚型
- IgG1
- Top Product
- Discover our top product PPP2CA Primary Antibody
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- 应用备注
- Optimal antibody dilution should be determined by titration, however as a guideline try, WB: 1,500. Detects a band of approximately 36 kDa (predicted molecular weight: 36 kDa)
- 说明
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Myeloma, fusion partners: X63-Ag8.653
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Purified antibody (from supernatant) containing PBS + 0.1 % sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Activation of AMP-activated protein kinase stimulates Na+,K+-ATPase activity in skeletal muscle cells." in: The Journal of biological chemistry, Vol. 287, Issue 28, pp. 23451-63, (2012) (PubMed).
: "Microcystin-LR (MCLR) induces a compensation of PP2A activity mediated by ?4 protein in HEK293 cells." in: International journal of biological sciences, Vol. 7, Issue 6, pp. 740-52, (2011) (PubMed).
: "A stress survival response in retinal cells mediated through inhibition of the serine/threonine phosphatase PP2A." in: The European journal of neuroscience, Vol. 32, Issue 3, pp. 322-34, (2010) (PubMed).
: "Generation of active protein phosphatase 2A is coupled to holoenzyme assembly." in: PLoS biology, Vol. 5, Issue 6, pp. e155, (2007) (PubMed).
: "Protein phosphatase 2A methyltransferase links homocysteine metabolism with tau and amyloid precursor protein regulation." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 27, Issue 11, pp. 2751-9, (2007) (PubMed).
: "Downregulation of protein phosphatase 2A carboxyl methylation and methyltransferase may contribute to Alzheimer disease pathogenesis." in: Journal of neuropathology and experimental neurology, Vol. 63, Issue 10, pp. 1080-91, (2004) (PubMed).
: "Altered expression levels of the protein phosphatase 2A ABalphaC enzyme are associated with Alzheimer disease pathology." in: Journal of neuropathology and experimental neurology, Vol. 63, Issue 4, pp. 287-301, (2004) (PubMed).
: "A novel and essential mechanism determining specificity and activity of protein phosphatase 2A (PP2A) in vivo." in: Genes & development, Vol. 17, Issue 17, pp. 2138-50, (2003) (PubMed).
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Activation of AMP-activated protein kinase stimulates Na+,K+-ATPase activity in skeletal muscle cells." in: The Journal of biological chemistry, Vol. 287, Issue 28, pp. 23451-63, (2012) (PubMed).
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- 抗原
- PPP2CA (Protein Phosphatase 2, Catalytic Subunit, alpha Isozyme (PPP2CA))
- 别名
- PP2A alpha (PPP2CA 产品)
- 别名
- PP2Ac antibody, PP2CA antibody, PP2Calpha antibody, RP-C antibody, PP2A antibody, R75353 antibody, Pp2a1 antibody, pp2ac antibody, zgc:110641 antibody, protein phosphatase 2 catalytic subunit alpha antibody, protein phosphatase 2 (formerly 2A), catalytic subunit, alpha isoform antibody, protein phosphatase 2, catalytic subunit, alpha isozyme antibody, protein phosphatase 2 catalytic subunit alpha L homeolog antibody, protein phosphatase 2, catalytic subunit, beta isozyme antibody, serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform antibody, PPP2CA antibody, Ppp2ca antibody, ppp2ca.L antibody, ppp2cb antibody, LOC471633 antibody, ppp2ca antibody
- 背景
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Synonyms:
PP2A alpha antibody,PP2A C antibody,PP2A-alpha antibody,PP2AA_HUMAN antibody,PP2Ac antibody,PP2CA antibody,PPP2CA antibody,Protein phosphatase 2, catalytic subunit, alpha isoform antibody,Replication protein C antibody - 基因ID
- 5515, 19052, 24672
- OMIM
- 176915
- UniProt
- P67775, P63330, P63331
- 途径
- PI3K-Akt Signaling, Mitotic G1-G1/S Phases, Hepatitis C, Toll-Like Receptors Cascades
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