alpha 2 Macroglobulin 抗体
(1 reference)-
- 抗原 See all alpha 2 Macroglobulin (A2M) 抗体
- alpha 2 Macroglobulin (A2M) (alpha-2-Macroglobulin (A2M))
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适用
- 人
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宿主
- 山羊
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克隆类型
- 多克隆
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标记
- This alpha 2 Macroglobulin antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), ELISA
- 产品特性
- Concentration Definition: by UV absorbance at 280 nm
- 免疫原
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a2-Macroglobulin [Human Plasma]
Immunogentype:Native - 亚型
- IgG
- Top Product
- Discover our top product A2M Primary Antibody
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anti-alpha-2-Macroglobulin (A2M) (AA 616-856) antibody
A2M 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-alpha-2-Macroglobulin (A2M) antibodyA2M 适用: 人 WB, IHC, IF 宿主: 兔 Monoclonal unconjugated
anti-alpha-2-Macroglobulin (A2M) (AA 616-856) antibodyA2M 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal C10 unconjugated
anti-alpha-2-Macroglobulin (A2M) (AA 1053-1214) antibodyA2M 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-alpha-2-Macroglobulin (A2M) (AA 1216-1467) antibodyA2M 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-alpha-2-Macroglobulin (A2M) (AA 1-1474) antibodyA2M 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-alpha-2-Macroglobulin (A2M) (AA 641-730) antibodyA2M 适用: 人 WB, ELISA, PLA 宿主: 小鼠 Monoclonal 2B5 unconjugated
anti-alpha-2-Macroglobulin (A2M) antibodyA2M 适用: 人 WB, IHC, ELISA, IP, IHC (p) 宿主: 山羊 Polyclonal unconjugated
anti-alpha-2-Macroglobulin (A2M) (AA 1-1474) antibodyA2M 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-alpha-2-Macroglobulin (A2M) (C-Term) antibodyA2M 适用: 人, 大鼠 WB, IHC, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Anti-alpha-2-macroglobulin antibody is suitable for ELISA, Western Blot and Immunohistochemistry applications. Anti-alpha-2-MACROGLOBULIN antibody should be optimized by the end user for the specific reactive conditions.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Restore with deionized water (or equivalent)
- 浓度
- 10.0 mg/mL
- 缓冲液
- 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
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: "Association of salivary alpha 2-macroglobulin levels and clinical characteristics in type 2 diabetes." in: Journal of diabetes investigation, Vol. 7, Issue 2, pp. 190-6, (2017) (PubMed).
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: "Association of salivary alpha 2-macroglobulin levels and clinical characteristics in type 2 diabetes." in: Journal of diabetes investigation, Vol. 7, Issue 2, pp. 190-6, (2017) (PubMed).
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- 抗原
- alpha 2 Macroglobulin (A2M) (alpha-2-Macroglobulin (A2M))
- 别名
- Alpha-2-Macroglobulin (A2M 产品)
- 别名
- A2MD antibody, CPAMD5 antibody, FWP007 antibody, S863-7 antibody, A2MAC1 antibody, A2m1 antibody, A2maa antibody, Mam antibody, A2mp antibody, A2M antibody, LOC733429 antibody, endod antibody, cpamd5 antibody, fwp007 antibody, s863-7 antibody, a2mb antibody, endodermin antibody, Alpha-2-M antibody, alpha-2-macroglobulin antibody, pregnancy-zone protein L homeolog antibody, alpha-2-macroglobulin S homeolog antibody, pregnancy zone protein antibody, alpha-2-macroglobulin-like antibody, A2M antibody, A2m antibody, LOC477699 antibody, pzp.L antibody, AZL_c00450 antibody, LOC100349077 antibody, a2m antibody, LOC100061656 antibody, LOC100090399 antibody, a2m.S antibody, LOC100469973 antibody, LOC100595735 antibody, PZP antibody, LOC100353095 antibody, LOC101122940 antibody, LOC101801552 antibody, LOC100911545 antibody
- 背景
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Alpha-2-Macroglobulin detects Macroglobulin. Alpha-2-MACROGLOBULIN is a large plasma protein found in the blood. It is produced by the liver, and is a major component of the alpha-2 band in protein electrophoresis. Alpha 2-Macroglobulin is the largest major nonimmunoglobulin protein in plasma. The alpha 2-macroglobulin molecule is synthesized mainly in liver, but also locally by macrophages, fibroblasts, and adrenocortical cells. Alpha 2 macroglobulin acts as an antiprotease and is able to inactivate an enormous variety of proteinases. It functions as an inhibitor of fibrinolysis by inhibiting plasmin and kallikrein. It functions as an inhibitor of coagulation by inhibiting thrombin. Alpha 2-macroglobulin may act as a carrier protein because it also binds to numerous growth factors and cytokines, such as platelet-derived growth factor, basic fibroblast growth factor, TGF-β, insulin, and IL-1β. No specific deficiency with associated disease has been recognized, and no disease state is attributed to low concentrations of Alpha 2 macroglobulin. The concentration of alpha 2 macroglobulin rises 10-fold or more in the nephrotic syndrome when other lower molecular weight proteins are lost in the urine. The loss of alpha 2 macroglobulin into urine is prevented by its large size. The net result is that alpha 2 macroglobulin reaches serum levels equal to or greater than those of albumin in the nephrotic syndrome, which has the effect of maintaining oncotic pressure. Antialpha-2-macroglobulin is ideal for investigators involved in serum component protein research.
Synonyms: A2M antibody, Alpha 2 M antibody, Alpha 2M antibody, CPAMD5 antibody, DKFZp779B086 antibody, FWP007 antibody, S863 7 antibody - 基因ID
- 2
- UniProt
- P01023
- 途径
- Lipid Metabolism
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