Nuclear Antigen 抗体
-
- 抗原 See all Nuclear Antigen (IPO-38) 抗体
- Nuclear Antigen (IPO-38)
-
适用
- 小鼠
-
宿主
- 小鼠
-
克隆类型
- 单克隆
-
标记
- This Nuclear Antigen antibody is un-conjugated
-
应用范围
- Immunohistochemistry (IHC), Immunoprecipitation (IP), ELISA, Western Blotting (WB)
- 产品特性
- Concentration Definition: by UV absorbance at 280 nm
- 过滤
- Sterile filtered
- 免疫原
-
A BALB/c mouse was immunized with spleen cells of a human patient with hairy cell leukemia.
Immunogentype:Native - 克隆位点
- IPO-38
- 亚型
- IgG
- Top Product
- Discover our top product IPO-38 Primary Antibody
-
anti-Nuclear Antigen (IPO-38) antibody
IPO-38 适用: 人, 小鼠, 大鼠 FACS, IF, IHC, StM 宿主: 小鼠 Monoclonal SPM260 unconjugated
anti-Nuclear Antigen (IPO-38) antibodyIPO-38 适用: 人, 小鼠, 大鼠 FACS, IF, IHC (p) 宿主: 小鼠 Monoclonal IPO-38 unconjugated
-
- 应用备注
- This antibody is suitable for ELISA, immunoprecipitation, western blotting and immunohistochemistry (frozen and formalin/paraffin). The antibody is reported to recognize a nuclear antigen that is present in the cytoplasm and nuclei of proliferating cells (paraformaldehyde fixed, Triton X-100 permeabilized). An increase of 400% is observed in cells in mitosis (determined by analysis of K562 cells synchronized with colcemide). IPO-38 does not block the binding of the Ki-67 antibody. Tonsilar tissue is typically used as a positive control.
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 浓度
- 1.0 mg/mL
- 缓冲液
- 0.02 M Potassium Phosphate, 0.5 M Sodium Chloride, pH 7.2
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
-
- 抗原
- Nuclear Antigen (IPO-38)
- 别名
- IPO-38 (IPO-38 产品)
- 背景
-
The specificity of mAb IPO-38 was demonstrated in different human and murine lymphoid and non-lymphoid cell lines. It does not react with mononuclear cells and granulocytes of healthy donors but does react with nuclei of blood cells of patients with different forms of leukemia and with cells from lymph nodes of patients with Hodgkin's disease and non-hodgkin's lymphoma. Also a positive reaction in nuclei of breast and colorectal tumor cells was demonstrated. IPO-38 may be a good marker of cellular proliferation during monitoring of tumor progression.
Synonyms: Non-histone chromosomal protein HMG-14 antibody, High-mobility group nucleosome-binding domain-containing protein 1 antibody, HMGN1 antibody, HMG14 antibody - 基因ID
- 15312
- NCBI登录号
- NP_032277
- UniProt
- P18608
-
