SARS-CoV-2 Envelope 抗体 (N-Term)
SARS-CoV-2 E
适用: SARS Coronavirus-2 (SARS-CoV-2), SARS Coronavirus (SARS-CoV)
ELISA, IHC, IF
宿主: 兔
Polyclonal
unconjugated
(9 references)-
- 抗原 See all SARS-CoV-2 Envelope (SARS-CoV-2 E) products
- SARS-CoV-2 Envelope (SARS-CoV-2 E)
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抗原表位
- N-Term
- 适用
- SARS Coronavirus-2 (SARS-CoV-2), SARS Coronavirus (SARS-CoV)
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This SARS-CoV-2 Envelope antibody is un-conjugated
- 应用范围
- ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
- 预测反应
- Predicted reactivity based on immunogen sequence: SARS-CoV Envelope proteins: (100%)
- 纯化方法
- Affinity chromatography purified via peptide column
- 免疫原
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Anti-SARS-CoV-2 (COVID-19, 2019-nCoV) Envelope antibody was raised against a peptide corresponding to 10 amino acids near the amino terminus of SARS-CoV-2 (COVID-19, 2019-nCoV) Envelope protein.
The immunogen is located within the first 50 amino acids of SARS-CoV-2 (COVID-19, 2019-nCoV) Envelope. - 亚型
- IgG
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anti-SARS-CoV-2 Envelope (SARS-CoV-2 E) (C-Term) antibody
SARS-CoV-2 E 适用: SARS Coronavirus-2 (SARS-CoV-2) WB 宿主: 山羊 Polyclonal unconjugated
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- 应用备注
- SARS-CoV-2 (COVID-19, 2019-nCoV) Envelope antibody can be used for the detection of SARS-CoV-2 (COVID-19, 2019-nCoV) Envelope protein in ELISA. It will detect 20 ng of free peptide at 1 μg/mL.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- The antibody is supplied in PBS containing 0.02% sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- The antibody can be stored at 4 ˚ C for three months and -20 ˚ C, stable for up to one year.
- 有效期
- 12 months
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: "The differing pathophysiologies that underlie COVID-19-associated perniosis and thrombotic retiform purpura: a case series." in: The British journal of dermatology, Vol. 184, Issue 1, pp. 141-150, (2021) (PubMed).
: "Reaction of Human Monoclonal Antibodies to SARS-CoV-2 Proteins With Tissue Antigens: Implications for Autoimmune Diseases." in: Frontiers in immunology, Vol. 11, pp. 617089, (2021) (PubMed).
: "Complement associated microvascular injury and thrombosis in the pathogenesis of severe COVID-19 infection: A report of five cases." in: Translational research : the journal of laboratory and clinical medicine, Vol. 220, pp. 1-13, (2020) (PubMed).
: "Analysis of complement deposition and viral RNA in placentas of COVID-19 patients." in: Annals of diagnostic pathology, Vol. 46, pp. 151530, (2020) (PubMed).
: "Strong homology between SARS-CoV-2 envelope protein and a Mycobacterium sp. antigen allows rapid diagnosis of Mycobacterial infections and may provide specific anti-SARS-CoV-2 immunity via the BCG ..." in: Annals of diagnostic pathology, Vol. 48, pp. 151600, (2020) (PubMed).
: "Structural and Functional Analysis of the D614G SARS-CoV-2 Spike Protein Variant." in: Cell, Vol. 183, Issue 3, pp. 739-751.e8, (2020) (PubMed).
: "A Novel In-Cell ELISA Assay Allows Rapid and Automated Quantification of SARS-CoV-2 to Analyze Neutralizing Antibodies and Antiviral Compounds." in: Frontiers in immunology, Vol. 11, pp. 573526, (2020) (PubMed).
: "Cytologic and molecular correlates of SARS-CoV-2 infection of the nasopharynx." in: Annals of diagnostic pathology, Vol. 48, pp. 151565, (2020) (PubMed).
: "Colorimetric Test for Fast Detection of SARS-CoV-2 in Nasal and Throat Swabs." in: ACS sensors, Vol. 5, Issue 10, pp. 3043-3048, (2020) (PubMed).
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: "The differing pathophysiologies that underlie COVID-19-associated perniosis and thrombotic retiform purpura: a case series." in: The British journal of dermatology, Vol. 184, Issue 1, pp. 141-150, (2021) (PubMed).
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- 抗原
- SARS-CoV-2 Envelope (SARS-CoV-2 E)
- 别名
- SARS-CoV-2 Envelope Protein (SARS-CoV-2 E 产品)
- 别名
- envelope protein antibody, E antibody
- 物质类
- Viral Protein
- 背景
- Coronavirus disease 2019 (COVID-19), formerly known as 2019-nCoV acute respiratory disease, is an infectious disease caused by SARS-CoV-2, a virus closely related to the SARS virus. The disease is the cause of the 2019–20 coronavirus outbreak. The structure of 2019-nCoV consists of the following: a spike protein (S), hemagglutinin-esterease dimer (HE), a membrane glycoprotein (M), an envelope protein (E) a nucleoclapid protein (N) and RNA. Envelope protein is a small polypeptide that contains at least one α-helical transmembrane domain. It involves in several aspects of the virus's life cycle, such as assembly, budding, envelope formation, and pathogenesis. E protein has membrane permeabilizing activity, which provides a possible rationale to inhibit in vitro ion channel activity of some synthetic coronavirus E proteins, and also viral replication.
- 基因ID
- 43740570
- NCBI登录号
- QHD43418
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