AFAP1L1 antibody can be used for detection of AFAP1L1 by Western blot at 1 μg/mL. Antibody can also be used for immunocytochemistry starting at 5 μg/mL. For immunofluorescence start at 20 μg/mL. Optimal dilutions for each application to be determined by the researcher.
限制
仅限研究用
状态
Liquid
浓度
1 mg/mL
缓冲液
PBS containing 0.02 % sodium azide
储存液
Sodium azide
注意事项
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
注意事项
As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
储存条件
4 °C/-20 °C
储存方法
AFAP1L antibody can be stored at 4 °C for three months and -20 °C, stable for up to one year.
有效期
12 months
抗原
AFAP1L1
(Actin Filament Associated Protein 1-Like 1 (AFAP1L1))
Synonym: Actin filament associated protein 1-like 1
The actin filament-associated protein 1 (AFAP1)-like 1 protein is one of three members in the AFAP1 family of adaptor proteins. Like AFAP1, AFAP1L1 is an actin binding protein that has a role in actin cytoskeleton arrangement, but AFAP1L1 is thought to have a unique function distinct from AFAP1. AFAP1L1 colocalizes with cortactin and localizes to invadosomes, highly dynamic, actin-rich adhesion structures harboring metalloproteases, suggesting that AFAP1L1 affects invadosome formation . Recent reports suggest that AFAP1L1 can be used as a prognostic marker for spindle cell sarcomas.