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LAMP1 抗体 (APC)

Name: LAMP1 抗体 (APC)
Brand: antibodies-online
SKU: ABIN1027703
Availability: OutOfStock

LAMP1 适用: 人, 小鼠, Non-Human Primate FACS 宿主: 小鼠 Monoclonal H4A3 APC

Flow cytometry analysis (intracellular staining) of human peripheral blood cells with anti-CD107a (H4A3) APC. (LAMP1 抗体 (APC))

FACS

Surface staining of human peripheral blood cells with anti-CD107a (H4A3) PE. (LAMP1 抗体 (APC))

FACS

2 images

(8 references)

产品编号 ABIN1027703

发货至: 中国

Datasheet as PDF

抗原 See all LAMP1 抗体

LAMP1 (Lysosomal-Associated Membrane Protein 1 (LAMP1))
适用
99

58

38

27

8

3

3

2

2

2

1

1

1
人, 小鼠, Non-Human Primate
宿主
61

55

18

1
小鼠
Compatible Secondaries
克隆类型
81

54
单克隆
标记
49

15

12

12

7

3

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
This LAMP1 antibody is conjugated to APC
应用范围
86

68

45

29

27

25

22

13

13

13

13

3

3

2

2

2

1

1
Flow Cytometry (FACS)

特异性

The mouse monoclonal antibody H4A3 recognizes an extracellular/luminal epitope of CD107a, an approximately 100-120 kDa glycoprotein expressed mainly on lysosomal, but also on the plasma membrane.

交叉反应（详细）

Human, Non-Human Primates, Mouse

纯化方法

Purified antibody is conjugated with activated allophycocyanin (APC) under optimum conditions and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.

免疫原

Human PBMC

克隆位点

H4A3

亚型

IgG1 kappa

Top Product

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anti-Lysosomal-Associated Membrane Protein 1 (LAMP1) (AA 80-280) antibody
LAMP1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated

anti-Lysosomal-Associated Membrane Protein 1 (LAMP1) (AA 301-417) antibody
LAMP1 适用: 人, 小鼠, 大鼠, 猴 WB, FACS, ELISA, ICC, IHC (p), IHC (fro), IF (p), IF (cc) 宿主: 兔 Polyclonal unconjugated

anti-Lysosomal-Associated Membrane Protein 1 (LAMP1) (AA 49-297) antibody
LAMP1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Lysosomal-Associated Membrane Protein 1 (LAMP1) antibody
LAMP1 适用: 人, 小鼠, Non-Human Primate WB, FACS, ICC, IHC (p), IHC (fro) 宿主: 小鼠 Monoclonal H4A3 unconjugated

anti-Lysosomal-Associated Membrane Protein 1 (LAMP1) antibody
LAMP1 适用: 大鼠 WB, IF, IP, ICC 宿主: 小鼠 Monoclonal Ly1C6 unconjugated

anti-Lysosomal-Associated Membrane Protein 1 (LAMP1) (AA 125-154) antibody
LAMP1 适用: 人, 小鼠 WB, IHC, IF, ELISA 宿主: 兔 Polyclonal unconjugated

anti-Lysosomal-Associated Membrane Protein 1 (LAMP1) antibody
LAMP1 适用: 人, 小鼠, 灵长类 WB, FACS, IHC, ICC, IHC (p), IHC (fro) 宿主: 小鼠 Monoclonal H4A3 unconjugated

anti-Lysosomal-Associated Membrane Protein 1 (LAMP1) antibody (FITC)
LAMP1 适用: 小鼠 WB, FACS, IHC, IP, IHC (p), IHC (fro) 宿主: 大鼠 Monoclonal FITC

anti-Lysosomal-Associated Membrane Protein 1 (LAMP1) antibody
LAMP1 适用: 人, Green Monkey WB, IF, IHC (p) 宿主: 小鼠 Monoclonal 3C3 unconjugated

anti-Lysosomal-Associated Membrane Protein 1 (LAMP1) antibody (Biotin)
LAMP1 适用: 人 FACS, IHC 宿主: 小鼠 Monoclonal H4A3 Biotin

应用备注

Flow cytometry: The reagent is designed for analysis of human blood cells using 10 μL reagent / 100 μL of whole blood or 10⁶ cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests. Intracellular and extracellular staining.

说明

The purified antibody is conjugated with cross-linked Allophycocyanin (APC) under optimum conditions. The conjugate is purified by size-exclusion chromatography and adjusted for direct use. No reconstitution is necessary.

限制

仅限研究用
溶解方式

No reconstitution is necessary.

缓冲液

Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Do not freeze.
Avoid prolonged exposure to light.

储存条件

4 °C

储存方法

Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
Majer, Vlaskova, Krol, Kalina, Kubanek, Stolnaya, Dvorakova, Elleder, Sikora: "Danon disease: a focus on processing of the novel LAMP2 mutation and comments on the beneficial use of peripheral white blood cells in the diagnosis of LAMP2 deficiency." in: Gene, Vol. 498, Issue 2, pp. 183-95, (2012) (PubMed).

Mao, Tu, Liu, Qin, Zheng, Chan, Lam, Peiris, Lau: "Inhibition of human natural killer cell activity by influenza virions and hemagglutinin." in: Journal of virology, Vol. 84, Issue 9, pp. 4148-57, (2010) (PubMed).

Yu, Gallegos, Marches, Zurawski, Ramilo, García-Sastre, Banchereau, Palucka: "Broad influenza-specific CD8+ T-cell responses in humanized mice vaccinated with influenza virus vaccines." in: Blood, Vol. 112, Issue 9, pp. 3671-8, (2008) (PubMed).

Tomescu, Chehimi, Maino, Montaner: "NK cell lysis of HIV-1-infected autologous CD4 primary T cells: requirement for IFN-mediated NK activation by plasmacytoid dendritic cells." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 179, Issue 4, pp. 2097-104, (2007) (PubMed).

Carlsten, Björkström, Norell, Bryceson, van Hall, Baumann, Hanson, Schedvins, Kiessling, Ljunggren, Malmberg: "DNAX accessory molecule-1 mediated recognition of freshly isolated ovarian carcinoma by resting natural killer cells." in: Cancer research, Vol. 67, Issue 3, pp. 1317-25, (2007) (PubMed).

Deetz, Hebbeler, Propp, Cairo, Tikhonov, Pauza: "Gamma interferon secretion by human Vgamma2Vdelta2 T cells after stimulation with antibody against the T-cell receptor plus the Toll-Like receptor 2 agonist Pam3Cys." in: Infection and immunity, Vol. 74, Issue 8, pp. 4505-11, (2006) (PubMed).

Furuta, Ikeda, Nakayama, Nakamura, Tanaka, Hamasaki, Himeno, Hamilton, August: "Expression of lysosome-associated membrane proteins in human colorectal neoplasms and inflammatory diseases." in: The American journal of pathology, Vol. 159, Issue 2, pp. 449-55, (2001) (PubMed).

Mane, Marzella, Bainton, Holt, Cha, Hildreth, August: "Purification and characterization of human lysosomal membrane glycoproteins." in: Archives of biochemistry and biophysics, Vol. 268, Issue 1, pp. 360-78, (1989) (PubMed).
抗原

LAMP1 (Lysosomal-Associated Membrane Protein 1 (LAMP1))

别名

CD107a (LAMP1 产品)

别名

CD107a antibody, LAMPA antibody, LGP120 antibody, AI196048 antibody, Lamp-1 antibody, LEP100 antibody, LAMP-1 antibody, LGP-A antibody, Lgpa antibody, Lysosome-associated membrane protein 1 antibody, cd107a antibody, lamp-1 antibody, lamp1 antibody, lampa antibody, lgp120 antibody, rexp76 antibody, lysosomal associated membrane protein 1 antibody, lysosomal-associated membrane protein 1 antibody, lysosomal-associated membrane protein 1 L homeolog antibody, LAMP1 antibody, Lamp1 antibody, lamp1.L antibody

背景

Lysosomal associated membrane protein 1,CD107a (lysosome-associated membrane protein-1, LAMP-1), together with LAMP-2, is a major constituent of lysosomal membrane, 1-2 % of total CD107a is found also on the plasma membrane. The LAMP proteins are involved in lysosome biogenesis and are required for fusion of lysosomes with phagosomes. Increased CD107a immunoreactivity is observed in neurones, and in glial cells surrounding senile plaques in Alzheimers disease cases and is localized mainly in medullary epithelial cells, single macrophages and lymphocytes in acute thymic involution. CD107a is a good marker of mast cell activation.,LAMP-1, LAMPA

基因ID

3916

UniProt

P11279

途径

Autophagy