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CD13 抗体 (Biotin)

ANPEP 适用: 人, Non-Human Primate FACS, IHC (fro), IP 宿主: 小鼠 Monoclonal WM15 Biotin
产品编号 ABIN1027683
发货至: 中国
  • 抗原 See all CD13 (ANPEP) 抗体
    CD13 (ANPEP) (Alanyl (Membrane) Aminopeptidase (ANPEP))
    适用
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    人, Non-Human Primate
    宿主
    • 94
    • 58
    • 13
    • 1
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    小鼠
    克隆类型
    • 112
    • 52
    单克隆
    标记
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    This CD13 antibody is conjugated to Biotin
    应用范围
    • 103
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    Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunoprecipitation (IP)
    特异性
    The antibody WM15 recognises an extracellular epitope of human CD13 cell surface glycoprotein, a 150 kDa molecule expressed on granulocytes, endothelial cells, epithelial cells and myeloid progenitors.
    交叉反应 (详细)
    Human, Non-Human Primates
    纯化方法
    Purified antibody is conjugated with biotin LC-NHS ester under optimum conditions and unconjugated antibody and free biotin are removed by size-exclusion chromatography.
    免疫原
    Human AML cells
    克隆位点
    WM15
    亚型
    IgG1
    Top Product
    Discover our top product ANPEP Primary Antibody
  • 应用备注
    Flow cytometry: Recommended dilution: 3-5 μg/mL.
    说明

    The purified antibody is conjugated with Biotin-LC-NHS under optimum conditions. The reagent is free of unconjugated biotin.

    限制
    仅限研究用
  • 浓度
    1 mg/mL
    缓冲液
    Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Do not freeze.
    Avoid prolonged exposure to light.
    储存条件
    4 °C
    储存方法
    Store at 2-8°C. Do not freeze.
  • McCormack, Muji?, Osdal, Bruserud, Gjertsen: "Multiplexed mAbs: a new strategy in preclinical time-domain imaging of acute myeloid leukemia." in: Blood, Vol. 121, Issue 7, pp. e34-42, (2013) (PubMed).

    Favaloro, Browning, Facey: "CD13 (GP150; aminopeptidase-N): predominant functional activity in blood is localized to plasma and is not cell-surface associated." in: Experimental hematology, Vol. 21, Issue 13, pp. 1695-701, (1993) (PubMed).

    Bradstock, Favaloro, Kabral, Kerr, Hughes, Berndt, Musgrove: "Human myeloid differentiation antigens identified by monoclonal antibodies: expression on leukemic cells." in: Pathology, Vol. 17, Issue 3, pp. 392-9, (1986) (PubMed).

    Bradstock, Favaloro, Kabral, Kerr, Hughes, Musgrove: "Myeloid progenitor surface antigen identified by monoclonal antibody." in: British journal of haematology, Vol. 61, Issue 1, pp. 11-20, (1985) (PubMed).

  • 抗原
    CD13 (ANPEP) (Alanyl (Membrane) Aminopeptidase (ANPEP))
    别名
    CD13 (ANPEP 产品)
    别名
    APN antibody, CD13 antibody, GP150 antibody, LAP1 antibody, P150 antibody, PEPN antibody, A2AP antibody, AAP antibody, ALPHA-2-PI antibody, API antibody, PLI antibody, AAT1 antibody, ALT1 antibody, GPT1 antibody, Gpt1 antibody, Apn antibody, pepN antibody, SC8E4A.13 antibody, 1300007J06Rik antibody, 2310022B03Rik antibody, ALT antibody, Gpt-1 antibody, AP-M antibody, AP-N antibody, Cd13 antibody, Apm antibody, KZP antibody, Lap1 antibody, rAPN antibody, APDE antibody, p150 antibody, anpep antibody, fb64c05 antibody, wu:fb64c05 antibody, zgc:136771 antibody, alanyl aminopeptidase, membrane antibody, serpin family F member 2 antibody, glutamic--pyruvic transaminase antibody, aminopeptidase N antibody, aminopeptidase antibody, aminopeptidase n antibody, glutamic pyruvic transaminase, soluble antibody, alanyl (membrane) aminopeptidase antibody, membrane alanyl aminopeptidase antibody, alanyl (membrane) aminopeptidase b antibody, alanyl aminopeptidase, membrane L homeolog antibody, ANPEP antibody, SERPINF2 antibody, GPT antibody, Gpt antibody, Apn2 antibody, Apn1 antibody, SCO2643 antibody, pepN antibody, Shewana3_0897 antibody, Alvin_1024 antibody, Ndas_3413 antibody, Saut_1544 antibody, Fbal_1877 antibody, ML5_3424 antibody, Despr_1988 antibody, Mesop_5365 antibody, Anpep antibody, LOC101744250 antibody, anpepb antibody, anpep.L antibody
    背景
    Alanyl aminopeptidase, membrane,CD13 (aminopeptidase N, APN) is a 150 kDa type II transmembrane zinc-binding ectopeptidase expressed on various cell types. This metalloprotease preferentially catalyzes removal of neutral amino acids from small peptides, thus activating or inactivating bioactive peptides. CD13 has also role in extracellular matrix degradation, antigen processing and signal transduction, is important in inflammatory responses, regulates intercellular contact, cell motility and vascularization. CD13 is involved in protection of leukemic cells against apoptosis and its expression associated with poor prognosis of carcinomas.,Aminopeptidase N, APN, PEPN, ANPEP, gp150, LAP1
    基因ID
    290
    UniProt
    P15144
    途径
    Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones
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